Automatic exchange of intracellular solution on Qube

Posted on May 25, 2016

The flexibility of Qube allows almost indefinite adaptation to user needs. For example, one might want to exchange the intracellular solution (IC) during an experiment. To illustrate this we changed all of the IC during hERG recordings and replenished half the columns with the original solution and the other half with an IC devoid of K+. The left panel shows the hERG current before the IC exchange. The right panel shows the preservation respectively abolishment of the hERG current in alternating columns as a result of exchanging the IC.

qube IC

Left panel: hERG current before exchange of intracellular solution. Right panel: Automatic exchange of intracellular solution show presence and absence of hERG currents in alternating columns