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    Antibacterial Polyelectrolyte Micelles for Coating Stainless Steel

    Year: 2012

    Journal: Langmuir, 2012, 28 (18), pp 7233–7241, 20120618

    Authors: Céline Falentin-Daudré†, Emilie Faure†, Tiziana Svaldo-Lanero‡, Fabrice Farina , Christine Jérôme†, Cécile Van De Weerdt§, Joseph Martial§, Anne-Sophie Duwez‡, and Christophe Detrembleur*†

    Last authors: Christophe Detrembleur

    Organizations: †Center for Education and Research on Macromolecules (CERM) and ‡Nanochemistry and Molecular Systems, Chemistry Department, University of Liège, Sart-Tilman B6a, 4000 Liège, Belgium § Laboratoire de Biologie Moléculaire et de Génie Génétique, Center of Biomedical Integrative Genoproteomics, CHU, B34 Sart-Tilman, B-4000 Liège, Belgium ArcelorMittal Liège Research, Bd de Colonster B57, 4000 Liège, Belgium

    Country: Belgium

    In this study, we report on the original synthesis and characterization of novel antimicrobial coatings for stainless steel by alternating the deposition of aqueous solutions of positively charged polyelectrolyte micelles doped with silver-based nanoparticles with a polyanion. The micelles are formed by electrostatic interaction between two oppositely charged polymers: a polycation bearing 3,4-dihydroxyphenylalanine units (DOPA, a major component of natural adhesives) and a polyanion (poly(styrene sulfonate), PSS) without using any block copolymer. DOPA units are exploited for their well-known ability to anchor to stainless steel and to form and stabilize biocidal silver nanoparticles (Ag0). The chlorine counteranion of the polycation forms and stabilizes biocidal silver chloride nanoparticles (AgCl). We demonstrate that two layers of micelles (alternated by PSS) doped with silver particles are enough to impart to the surface strong antibacterial activity against gram-negative E. coli. Moreover, micelles that are reservoirs of biocidal Ag+ can be easily reactivated after depletion. This novel water-based approach is convenient, simple, and attractive for industrial applications.