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Characterization of structural changes in aptamer films for controlled release nanodevices

Year: 2012

Journal: Chem. Commun., 2012,48, 10087-10089, 20130118

Authors: M. Belén Serrano-Santos *a, Eduard Llobet a, Veli C. Özalp b, Thomas Schäfer bc

Last authors: Thomas Schäfer

Organizations: a EMaS, Department of Electronic, Electric and Automation Engineering, University Rovira i Virgili, Avda. Països Catalans 26, 43007 Tarragona, Spain. E-mail: mariabelen.serrano@urv.cat b NanoBioSeparations Group, POLYMAT, University of the Basque Country UPV/EHU, Avda. Tolosa 72, 20018 Donostia-San Sebastián, Spain. E-mail: thomas_schafer@ehu.es; Fax: +34 943015347; Tel: +34 943018266 c Basque Foundation for Science, Ikerbasque, Bilbao, Spain

Country: Spain

The dimension of the conformational changes of DNA-aptamers which can be used as stimulus-responsive gate-keepers in controlled delivery nanodevices has been determined by acoustic wave-based sensors upon molecular recognition of a small-sized target, adenosine-5′-monophosphate (AMP).