Development of a Biocompatible Lubricous Coating for Biomedical Applications

A biocompatible lubricious surface coating based on poly(L-lysine) or L-lysine and hyaluronic acid multilayers was investigated. No chemical modification of polyelectrolytes was necessary and the final architecture was obtained using the layer-by-layer deposition method. Investigation of coating morphology and coating thickness show that all tested coating compositions result in a very smooth and homogenous coating with thicknesses between 0.6 and 2 mu m.