Year: 2013
Journal: J. Am. Chem. Soc., 2013, 135 (15), pp 5513–5516, 20130628
Authors: Ji-Hun Seo † , Sachiro Kakinoki ‡ , Yuuki Inoue § , Tetsuji Yamaoka ‡ , Kazuhiko Ishihara § , and Nobuhiko Yui *†
Last authors: Nobuhiko Yui
Organizations: † Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda, Tokyo 101-0062, Japan ‡ Department of Biomedical Engineering, National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka 565-8565, Japan § Department of Materials Engineering, The University of Tokyo, Bunkyo, Tokyo 113-8656, Japan Japan Science and Technology Agency (JST), CREST, Chiyoda, Tokyo 102-0076, Japan
Country: Japan
The rapid response of integrin β1 molecules to an RGD peptide on a dynamic polyrotaxane surface was successfully induced. As a result, RGD peptides introduced on a highly dynamic cyclodextrin molecule enhanced the frequency of contact with specific integrin molecules on the cell membrane at the early stage of material–cell interactions.
