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    Interactions between suitably functionalised conformationally distinct benzanilides and phospholipid monolayers

    Year: 2012

    Journal: Soft Matter, 2012, 8, 3258-3264, 20131009

    Authors: Sarah R. Dennison, Zaheer Akbar, David A. Phoenix, Timothy J. Snape

    Organizations: aSchool of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, PR1 2HE, UK; Directorate, Adelphi Building, University of Central Lancashire, Preston, PRI 2 HE, UK

    The interaction between phospholipid monolayers and two conformationally distinct benzanilides possessing suitably positioned n-octyl groups was examined. The results obtained suggest a strong link between conformation and membrane binding and that this is driven by amphiphilicity.