Interference of citrate-stabilized gold nanoparticles with b2-microglobulin oligomeric association

Protein fibrillation is involved in many serious diseases, and protein

oligomers are proved to be precursors of amyloid fibrils. NMR and

QCMD experiments allowed us to establish that the interaction

between citrate-stabilized gold nanoparticles and a paradigmatic

amyloidogenic protein, b2-microglobulin, is able to interfere with

protein association into oligomers.