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Liposome fusion on proteinaceous S-layer lattices triggered via β-diketone ligand–europium(III) complex formation

Year: 2011

Journal: Soft Matter, 2011, 7, 5514-5518, 20120104

Authors: Schrems A 1, Larisch VD 1, Stanetty C 2, Dutter K 1, Damiati S 1, Sleytr UB 1, Schuster B 1 *

Last authors: Bernhard Schuster

Organizations: 1 Department of NanoBiotechnology, University of Natural Resources and Life Sciences, Muthgasse 11, 1190, Vienna, Austria. E-mail: bernhard.schuster@boku.ac.at 2 Department of Chemistry, University of Natural Resources and Life Sciences, Muthgasse 18, 1190, Vienna, Austria

Country: Austria

The present study describes a method for generating solid supported lipid membranes. Liposomes containing β-diketone ligands were chemically bound to crystalline surface (S-) layer proteins which entirely covered the gold sensors. These ligands formed complexes with added europium(III) ions and triggered fusion/rupture of the liposomes resulting in planar supported lipid bilayers.