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Liquified chitosan–alginate multilayer capsules incorporating poly(L-lactic acid) microparticles as cell carriers

Year: 2013

Journal: Soft Matter, 2013,9, 2125-2130, 20130324

Authors: Clara R. Correia , Praveen Sher , Rui L. Reis and João F. Mano

Last authors: João F. Mano

Organizations: 3B's Research Group – Biomaterials, Biodegradables and Biomimetics, Avepark, Zona Industrial da Gandra, S. Cláudio do Barco, 4806-909 Taipas, Guimarães, Portugal. and ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal.

Country: Portugal

We report the development of liquified multilayer hierarchical capsules capable of providing cell adhesion sites to the encapsulated cells. The proof of principle is demonstrated with the example of a chitosan–alginate shell via layer-by-layer assembly, encapsulating cells adhered to the functionalized surface of poly(L-lactic acid) microparticles.