Contact
    Start Publications Nano-Graphene Oxide Functionalized Bioactive Poly(lactic acid) ...
    ←  Publication Finder
    KSV NIMA

    Nano-Graphene Oxide Functionalized Bioactive Poly(lactic acid) and Poly(epsilon-caprolactone) Nanofibrous Scaffolds

    Year: 2018

    Journal: Materials, Volume 11, APR

    Authors: Wu, Duo; Samanta, Archana; Srivastava, Rajiv K.; Hakkarainen, Minna

    Organizations: China Scholarship Council (CSC)

    Keywords: PLA; PCL; graphene oxide; scaffold; mechanical properties; biomineralization

    A versatile and convenient way to produce bioactive poly(lactic acid) (PLA) and poly(epsilon-caprolactone) (PCL) electrospun nanofibrous scaffolds is described. PLA and PCL are extensively used as biocompatible scaffold materials for tissue engineering. Here, biobased nano graphene oxide dots (nGO) are incorporated in PLA or PCL electrospun scaffolds during the electrospinning process aiming to enhance the mechanical properties and endorse osteo-bioactivity. nGO was found to tightly attach to the fibers through secondary interactions. It also improved the electrospinnability and fiber quality. The prepared nanofibrous scaffolds exhibited enhanced mechanical properties, increased hydrophilicity, good cytocompatibility and osteo-bioactivity. Therefore, immense potential for bone tissue engineering applications is anticipated.
    View publication