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    Supported Lipid Membranes

    Year: 2003

    Journal: Materials Today, November 2003, p. 32-37, 20100827

    Authors: Richter R.P., Him J.L.K., Brisson A.

    Last authors: Alain Brisson

    Organizations: Laboratoire d’Imagerie Moléculaire et Nano-Bio-Technologie, Institut Europeen de Chimie et Biologie, Université Bordeaux 1, 33607 Pessac Cedex, France

    Country: France

    This review focuses on a versatile approach that combines the formation of solid-supported lipid bilayers (SLBs)b y deposition of lipid vesicles with the adsorption of proteins and formation of ordered protein layers via specific interaction with ligands incorporated in the SLBs. This approach provides access to basic aspects of membrane biophysics, membrane-protein interactions and molecular ordering in two dimensions. It may also constitute a strategy for the design of biofunctional surfaces at the nanoscale.