Contact
    Start Publications Thermoresponsive Reversible Behavior of Multistimuli ...
    ←  Publication Finder
    Attension

    Thermoresponsive Reversible Behavior of Multistimuli Pluronic-Based Pentablock Copolymer at the Air-Water Interface

    Year: 2007

    Journal: Langmuir, 2007, 23 (1), pp 25–30, 20111221

    Authors: Sergiy Peleshanko, Kyle D. Anderson, Matthew Goodman, Michael D. Determan, Surya K. Mallapragada, and Vladimir V. Tsukruk

    Organizations: Department of Materials Science and Engineering, Iowa State University, Ames, Iowa 50011, Department of Chemical and Biological Engineering, Iowa State University and Ames Laboratory, Ames, Iowa 50011, and School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332

    Surface behavior of the pH- and thermoresponsive amphiphilic ABCBA pentablock copolymer has been studied with respect to the environmental conditions. We demonstrate that the pentablock copolymer poly((diethylaminoethyl methacrylate)-b-(ethylene oxide)-b-(propylene oxide)-b-(ethylene oxide)-b-(diethylaminoethyl methacrylate)) possesses reversible temperature changes at the air−water interface in a narrow pH range of the water subphase. Significant diversity in the surface morphology of pentablock copolymer monolayers at different pH and temperatures observed were related to the corresponding reorganization of central and terminal blocks. Remarkable reversible variations of the surface pressure observed for the Langmuir monolayers at pH 7.4 in the course of heating and cooling between 27 and 50 °C is associated with conformational transformations of terminal blocks crossing the phase line in the vicinity of the lower critical solution temperature point. The observed thermoresponsive surface behavior can be exploited for modeling of the corresponding behavior of pentablock copolymers adsorbed onto various biointerfaces for intracellular delivery for deeper understanding of stimuli-responsive transformations relevant to controlled drug and biomolecules release and retention.