Contact
    Start Publications Application of Heat-Enhancement for Improving the Sensitivity ...
    ←  Publication Finder
    QSense

    Application of Heat-Enhancement for Improving the Sensitivity of Quartz Crystal Microbalance

    Journal: Biosensors-Basel, Volume 12, AUG

    Authors: Song, Chenglong; Ma, Zhihao; Li, Chenglong; Zhang, Hongxing; Zhu, Zhiqiang; Wang, Jie

    Organizations: Natural Science Foundation of Jiangsu Province [BK20150490]

    Keywords: quartz crystal microbalance; resonant frequency; single nucleotide polymorphism (SNP)

    The use of quartz crystal microbalance in trace mass detection is restricted by unsatisfactory sensitivity, especially in damping media, due to the worsening of the quality factor of the damping resonator. The enhancement of the sensor performance could be realized by increasing the innate resonant frequency of quartz oscillators. Herein, increased working temperature of QCM systems was proved to bring an enhancement of the original resonant frequency. In addition, the measurement of ion osmotic pressure, single layer formation and single nucleotide polymorphism (SNP) at different temperatures demonstrated that an increased working temperature could enhance the sensitivity and accuracy, suggesting a potential application in a series of trace detections.
    View publication