Contact
    Start Publications Mixed Matrix Membranes Adsorbers (MMMAs) for the Removal of ...
    ←  Publication Finder
    Attension

    Mixed Matrix Membranes Adsorbers (MMMAs) for the Removal of Uremic Toxins from Dialysate

    Year: 2022

    Journal: Membranes, Volume 12, FEB

    Authors: De Pascale, Matilde; De Angelis, Maria Grazia; Boi, Cristiana

    Organizations: Italian National Ministry of University and Research; RSE Saltire Facilitation Workshop Award 1898 Susmedia: -Engineering membrane adsorbers for sustainable dialysis

    Keywords: porous mixed matrix membrane adsorbers; uremic toxins; urea; zeolite; activated carbon; water purification; dialysis

    We developed Mixed Matrix Membrane Adsorbers (MMMAs) formed by cellulose acetate and various sorbent particles (activated carbon, zeolites ZSM-5 and clinoptilolite) for the removal of urea, creatinine and uric acid from aqueous solutions, to be used in the regeneration of spent dialysate water from Hemodialysis (HD). This process would allow reducing the disproportionate amount of water consumed and permits the development of closed-loop HD devices, such as wearable artificial kidneys. The strategy of MMMAs is to combine the high permeability of porous membranes with the toxin-capturing ability of embedded particles. The water permeability of the MMMAs ranges between 600 and 1500 L/(h m(2) bar). The adsorption of urea, the limiting toxin, can be improved of about nine times with respect to the pure cellulose acetate membrane. Flow experiments demonstrate the feasibility of the process in a real HD therapy session.
    View publication