Contact
    Start Publications One Step Fabrication and Application of Antibacterial ...
    ←  Publication Finder
    Attension

    One Step Fabrication and Application of Antibacterial Electrospun Zein/Cinnamon Oil Membrane Wound Dressing via In situ Electrospinning Process

    Year: 2021

    Journal: Chem. Res. Chin. Univ., Volume 37, JUN, page 464–469

    Authors: Qin, Mei; Liu, Daqing; Dai, Zhang; Meng, Xin; Liu, Guosai; Liu, Hao; Huang, Xiaowei; Yan, Xu; Chen, Shaojuan

    Organizations: Postdoctoral Science Foundation of China [2020M671998]; Fund of the State Key Laboratory of Bio-Fibers and EcoTextiles(Qingdao University) of China [ZKT35]; National Natural Science Foundation of China [51703102]

    Keywords: In situ electrospinning; Antibacterial wound dressing; Zein; Cinnamon oil

    Antibacterial wound dressing can benefit the wound healing by preventing bacterial infection, especially for the electrospun ones due to their porous structures and easily loading antibacterial drugs. However, it is challenging to apply the antibacterial electrospun wound dressing to covering the wound conveniently and safely. Here, we presented one step fabrication and application of antibacterial electrospun zein/cinnamon oil wound dressing via a handheld electrospinning setup. The prepared zein/cinnamon oil wound dressing showed gas permeability of (76.1-5.45) mm/s, hydrophilicity with zero body fluid contact angle, swelling stability after 24 h as well as antibacterial zones over 5 cm against both E. coli and S. aureus bacteria. Moreover, in situ electrospinning process can deposit the electrospun zein/cinnamon oil fibers directly onto the wound, meantime forming a wound dressing. The mice cut-wound model experiment demonstrated that the one step in situ fabrication and application of zein/cinnamon oil wound dressing could nearly heal the wound within 11 d.
    View publication