Contact
    Start Publications Preparation and Evaluation of Nanofibrous Hydroxypropyl ...
    ←  Publication Finder
    Attension

    Preparation and Evaluation of Nanofibrous Hydroxypropyl Cellulose and beta-Cyclodextrin Polyurethane Composite Mats

    Year: 2020

    Journal: Nanomaterials, Volume 10, APR

    Authors: Gradinaru, Luiza Madalina; Barbalata-Mandru, Mihaela; Drobota, Mioara; Aflori, Magdalena; Spiridon, Maria; Pircalabioru, Gratiela Gradisteanu; Bleotu, Coralia; Butnaru, Maria; Vlad, Stelian

    Organizations: European Regional Development FundEuropean Commission [86/8.09.2016, MySMIS 105689]

    Keywords: biocompatibility; cytotoxicity; electrospinning; nanofibers; polyurethane composites

    A series of nanofibrous composite mats based on polyurethane urea siloxane (PUUS), hydroxypropyl cellulose (HPC) and beta-cyclodextrin (beta-CD) was prepared using electrospinning technique. PUUS was synthesized by two steps solution polymerization procedure from polytetramethylene ether glycol (PTMEG), dimethylol propionic acid (DMPA), 4,4'-diphenylmethane diisocyanate (MDI) and 1,3-bis-(3-aminopropyl) tetramethyldisiloxane (BATD) as chain extender. Then, the composites were prepared by blending PUUS with HPC or beta CD in a ratio of 9:1 (w/w), in 15% dimethylformamide (DMF). The PUUS and PUUS based composite solutions were used for preparation of nanofibrous mats. In order to identify the potential applications, different techniques were used to evaluate the chemical structure (Fourier transform infrared-attenuated total reflectance spectroscopy FTIR-ATR), morphological structure (Scanning electron microscopy-SEM and Atomic force microscopy-AFM), surface properties (contact angle, dynamic vapors sorption-DVS), mechanical characteristics (tensile tests), thermal (differential scanning calorimetry-DSC) and some preliminary tests for biocompatibility and microbial adhesion.
    View publication