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The Tuning of Chitosan's Hydrophilicity by Changing the PEG Content Grafted on the Chitosan Backbone

Year: 2020

Journal: Mater. Plast., Volume 57, DEC, page 145–154

Authors: Ailincai, Daniela

Organizations: Romanian National Authority for Scientific Research MEN - UEFISCDIConsiliul National al Cercetarii Stiintifice (CNCS)Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii (UEFISCDI) [PN-III-P1-1.1-PD-2019-1021, H2020-MSCA-RISE-2019, 873123]

Keywords: chitosan; PEGylation; hydrophilicity; imines; amines

The study presents the synthesis and characterization of two series of hydrophilic chitosan derivatives, based on imine or amine linkage through PEGylation. The impact of PEGylation on the morphology and supramolecular architecture along with the wettability were studied. The obtained results proved that PEGylation is an appropriate method for tuning chitosan's hydrophilicity. Adding to that, the properties of the derivatives can be designed according to the targeted application.