In this webinar, Federica Sebastini, PhD in chemistry from the University of Reading, UK, will present how she and her collaborators have developed a time and cost-effective method to screen a wide range of LNP formulations and select the most promising candidates for in vitro and in vivo studies. By exploring two approaches, she investigated the binding affinity between LNPs and serum proteins. Sensing was done using Quartz Crystal Microbalance with Dissipation (QCM-D) but the approach is extendable to other surface sensing techniques such as Surface Plasmon Resonance (SPR) or ellipsometry.
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