Year: 2014
Journal: Analyst, 2014,139, 5350-5353, 20141010
Authors: E. Nilebäck,L. Enochson,N. Altgärde,M. Schnabelrauch,A. Lindahl,S. Svedhem *A. Kunze *
Last authors: A. Kunze
Organizations: a Dept. of Appl. Physics, Chalmers University of Technology, Göteborg, Sweden b Biolin Scientific AB, Västra Frölunda, Sweden c Dept. of Clinical Chemistry and Transfusion Medicine, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden d Biomaterials Department, INNOVENT e.V., 07745 Jena, Germany e Inst. of Physical Chemistry, Univerisity of Götttingen, Göttingen, Germany
Country: Sweden, Sverige, Germany
The interaction of human-derived chondrocytes and thin hyaluronan layers was studied using the quartz crystal microbalance with dissipation (QCM-D) technique combined with light microscopy. This approach allowed unique real-time monitoring of the interface between the cells and the sensor surface. Our results suggest that the hyaluronan layer is rapidly degraded by chondrocytes.
