Contact
    Start Publications Enantiospecificity of sterol-lipid interactions: first evidence ...
    ←  Publication Finder
    Attension

    Enantiospecificity of sterol-lipid interactions: first evidence that the absolute configuration of cholesterol affects the physical properties of cholesterol-sphingomyelin membranes

    Year: 2001

    Journal: Chem. Commun., 2001, 1192-1193, 20111221

    Authors: S. Lalitha, A. Sampath Kumar, Keith J. Stine and Douglas F. Covey

    Organizations: a Division of Bioorganic Chemistry, Department of Molecular Biology and Pharmacology, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, Missouri, 63110, USA. E-mail: dcovey@molecool.wustl.edu b Department of Chemistry and Center for Molecular Electronics, University of Missouri St. Louis, St. Louis, Missouri, 63121, USA. E-mail: kstine@jinx.umsl.edu

    Results from monolayer studies using the enantiomers of cholesterol (nat- and ent-cholesterol) and egg yolk sphingomyelin show for the first time that enantiospecific interactions between sterols and lipids can affect the physical properties of membranes.