Contact
    Start Publications Langmuir–Blodgett films of polyaniline for low density ...
    ←  Publication Finder
    KSV NIMA

    Langmuir–Blodgett films of polyaniline for low density lipoprotein detection

    Year: 2010

    Journal: Thin Solid Films, 2010, 519 (3), 1110-1114, 20131009

    Authors: Zimple Matharu, G. Sumana, Vinay Gupta, B.D. Malhotra

    Organizations: Department of Science and Technology Centre on Biomolecular Electronics, Biomedical Instrumentation Section, National Physical Laboratory (CSIR), Dr. K. S. Krishnan Marg, New Delhi-110012, India; Department of Physics and Astrophysics, University of Delhi, Delhi-110007, India

    Langmuir–Blodgett (LB) films of polyaniline (PANI) were utilized for the fabrication of impedimetric immunosensor for detection of human plasma low density lipoprotein (LDL) by immobilizing anti-apolipoprotein B (AAB) via EDC–NHS coupling. The modified electrodes were characterized by electrochemical impedance spectroscopy (EIS) and scanning electron microscopy. AAB/PANI–SA LB immunoelectrodes studied by EIS spectroscopy revealed detection of LDL in the wide range of 0.018 μM (6 mg/dl) to 0.39 μM (130 mg/dl), covering the physiological range in blood, with a sensitivity of 11.25 kΩ μM− 1.