Contact
    Start Publications Lichenysin-geminal amino acid-based surfactants: Synergistic ...
    ←  Publication Finder
    KSV NIMA

    Lichenysin-geminal amino acid-based surfactants: Synergistic action of an unconventional antimicrobial mixture

    Year: 2017

    Journal: Colloid Surf. B-Biointerfaces, Volume 149, JAN 1, page 38–47

    Authors: Coronel-Leon, Jonathan; Pinazo, Aurora; Perez, Lourdes; Jose Espuny, Ma; Ma Marques, Ana; Manresa, Angeles

    Organizations: Ministerio de Economia y Competitividad, Spain [CTQ2014-59632-R, CTQ2013-41514-P, MAT2012-38047-CO2-02]; IV Pla de Recerca de Catalunya (Generalitat de Catalunya) grant [2014SGR-534]; Ecuador's Government for a SENESCYT-ESPOL grant

    Keywords: Antimicrobial properties; Lichenysin; Flow cytometry; Transmission electron microscopy; Potassium leakage; Gemini surfactants; Arginine; Listeria nonocytogenes; Escherichia coli

    Recently it has been demonstrated that catanionic mixtures of oppositely charged surfactants have improved physicochemical-biological properties compared to the individual components. Isotherms of mixtures of an anionic biosurfactant (lichenysin) and a cationic aminoacid surfactant (C-3(LA)(2)) indicate a strong interaction suggesting the formation of a new "pseudo-surfactant". The antimicrobial properties of the mixture lichenysin and C-3(LA)(2) M80:20, indicate a synergistic effect of the components. The mechanism of action on the bacterial envelope was assessed by flow cytometry and Transmission Electron Microscopy. (C) 2016 Elsevier B.V. All rights reserved.
    View publication