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Self-assembly of anisotropic tobacco mosaic virus nanoparticles on gold substrate

Year: 2011

Journal: SCIENCE CHINA Chemistry, Volume 54, Number 1, p 137-143, 20110317

Authors: Peng B. 1, Liu N. 2, Lin Y. 1 3, Wang L. 1, Zhang W. 2, Niu Z. 3, Wang Q. 3, Su Z. 1

Last authors: ZhaoHui Su

Organizations: 1 State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry,Chinese Academy of Sciences, Changchun 130022, China 2 State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China 3 Department of Chemistry and Biochemistry and Nanocenter, University of South Carolina, Columbia, SC 29208, USA

Country: China

A facile approach to assembled virus film with tunable structure is presented. Rod-like tobacco mosaic virus (TMV) was selected as the prototype in this study for its anisotropic structural feature. TMV can either "lie down" or "stand up" on gold substrate by tuning the solution pH. A quartz crystal microbalance with dissipation monitoring was used to monitor the pH-dependent self-assembly behavior of TMV nanoparticles, and atomic force microscopy and single molecule force spectroscopy further confirmed the different assembly structures.