Contact
    Start Publications Surface enhancement of a molecularly imprinted polymer film ...
    ←  Publication Finder
    Attension

    Surface enhancement of a molecularly imprinted polymer film using sacrificial silica beads for increasing L-arabitol chemosensor sensitivity and detectability

    Year: 2017

    Journal: J. Mat. Chem. B, Volume 5, AUG 21, page 6292–6299

    Authors: Dabrowski, Marcin; Cieplak, Maciej; Noworyta, Krzysztof; Heim, Matthias; Adamkiewicz, Witold; Kuhn, Alexander; Sharma, Piyush Sindhu; Kutner, Wlodzimierz

    Organizations: Polish National Science Centre (NCN) [2011/N/ST4/03491]; NCN [2011/03/D/ST4/02596]; European Regional Development Fund [POIG.01.01.02-00-008/08]; European 7th Framework Programme [FP7-REGPOT-CT-2011-285949-NOBLESSE]

    Molecular imprinting in polymers leads, among others, to synthetic receptors of high selectivity, comparable to that of their biological counterparts. Deposition of a thin non-porous molecularly imprinted polymer (MIP) film directly on a transducer surface enables fabrication of chemosensors for various health relevant biocompounds. However, the sensitivity of a chemosensor with such an MIP film as the recognition unit is limited, mostly because of slow analyte diffusion through this film. Herein, a simple procedure was developed to enhance, in a controlled way, the active surface area of an L-arabitol imprinted polymer film. For this, a macroporous MIP-(L-arabitol) film was synthesized and simultaneously deposited on a gold electrode of a quartz crystal resonator transducer by potentiodynamic electropolymerization. This large surface area film effectively enhanced analytical signals of mass changes at a quartz crystal microbalance. Hence, the L-arabitol limit of quantification was B16-fold better than that of the corresponding non-porous MIP film of the same mass.
    View publication