The Bioactivity and Stability Evaluation of the PPy/Ca-P Hybrid Films on Titanium Alloy Implant
Year: 2016
Journal: Mater. Plast.
Authors: Pirvu, C; Mindroiu, M; Craciunescu, O; Constantin, D
This study has been carried out to investigate a new method to improve metallic implant bioactivity for osseointegration by producing a calcium phosphate (Ca-P) surface layer using an immersion process in the Simulated Body Fluid (SBF) of Polypyrrole (PPy) and Polypyrrole/poly(sodium-4styrensulfonate) (NaPSS) conductive hybrid polymers electrochemically synthesized on Ti6A17Nb alloy. As formed PPy/Ca-P and PPy/ PSS-/Ca-P films were characterized electrochemically by Cyclic Voltammetry (CV), Tafel plots and spectroscopically using FT-IR technique. Also, in vitro cytotoxicity of these new organic/inorganic hybrids films was evaluated by yellow 3- (4,5-dimethylthiazolyI-2)-2,5-diphenyltetrazolium bromide (MTT) assay after cultivation in a primary culture of osteoblast cells. The PPy/Ca-P hybrid film showed the best electrochemical stability and the highest value of cell viability.
