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Vitroceramic interface deposited on titanium substrate by pulsed laser deposition method

Year: 2016

Journal: Int. J. Pharm.

Authors: Voicu, G; Miu, D; Dogaru, I; Jinga, SI; Busuioc, C

Pulsed laser deposition (PLD) method was used to obtain biovitroceramic thin film coatings on titanium substrates. The composition of the targets was selected from SiO2-CaO-P2O5-(CaF2) systems and the corresponding masses were prepared using the sol-gel method. The depositions were performed in oxygen atmosphere (100 mTorr), while the substrates were heated at 400 degrees C. The PLD deposited films were analysed through different experimental techniques: X-ray diffraction, scanning (SEM, EDX) and transmission (HRTEM, SAED) electron microscopy and infra-red spectroscopy coupled with optical microscopy. They were also biologically tested by in vitro cell culture and the contact angle was determined. The bioevaluation results indicate a high biocompatibilty of the obtained materials, demonstrating their potential use for biomedical applications. (C) 2015 Elsevier B.V. All rights reserved.