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    Characteristics of hybrid chitosan/phospholipid-sterol, peptide coatings on plasma activated PEEK polymer

    Year: 2021

    Journal: Mater. Sci. Eng. C-Mater. Biol. Appl., Volume 120, JAN

    Authors: Przykaza, K.; Jurak, M.; Wiacek, A. E.; Mroczka, R.

    Organizations: European Regional Development Fund in the framework of the Polish Innovation Economy Operational Program [POIG.02.01.00-06-024/09]; European Regional Development Fund [POPW.01.03.00-06-003/09-00]

    Keywords: PEEK polymer; Plasma activation; Chitosan coating; Langmuir and Langmuir-Blodgett films; Cyclosporine A; Wettability; Surface free energy; TOF-SIMS analysis

    In this paper, we propose a method of obtaining multi-component surface coatings on PEEK polymer, which is becoming increasingly interested in a very wide branch of medicine orthopedics. Thanks to the plasma techniques used and due to the presence of chitosan, the materials obtained are characterized by sterility, antisepticity, can accelerate wound healing, and serve as a drug delivery system directly to the tissues in need. In addition, the use of ternary Langmuir-Blodgett (lipid-sterol, peptide) films has resulted in significant change of surfaces polarity. The physico-chemical properties of the ternary Langmuir films obtained on the water subphase were tested exploiting Langmuir trough and a Brewster angle microscope. Then they were transferred to the modified surfaces of the solid PEEK polymer, where changes in wettability as well as surface free energy were determined by the type of substrate/coating and the hybrid composition. Additionally, surface chemistry was studied applying time of flight secondary ion mass spectrometry.
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