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    Electrospinning Highly Concentrated Sodium Alginate Nanofibres without Surfactants by Adding Fluorescent Carbon Dots

    Year: 2020

    Journal: Nanomaterials, Volume 10, MAR

    Authors: Yu, Junke; Zhao, Zhihui; Sun, Jianxin; Geng, Cunzhen; Bu, Qingxu; Wu, Dawei; Xia, Yanzhi

    Organizations: National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [51303089]; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [20110491557, 2012T50597]; Postdoctoral Innovation Foundation of Shandong Province [201102039]; Changjiang Scholars and Innovative Research Team in UniversityProgram for Changjiang Scholars & Innovative Research Team in University (PCSIRT) [IRT_14R30]; Taishan Scholar Program of Shandong Province [tspd20181208]

    Keywords: sodium alginate; electrospinning; nanofibres

    In this study, sodium alginate (SA) nanofibres were obtained by electrospinning via the assistance of traditional poly(ethyl oxide) (PEO) and dimethyl sulfoxide (DMSO) with a high SA/PEO ratio of up to 94:6. However, surfactants with more or less toxicities were replaced by nontoxic and fluorescent carbon dots (CDs) to improve spinnability. Experimental details were conducted by fixing the ratio of SA/PEO to 90:10. Then, the electrospinning products of solutions with different compositions were observed with scanning electron microscopy. Properties such as conductivity, surface tension and rheology of the solutions were investigated to determine the key influencing factors. Moreover, since CDs have excellent fluorescence properties, the fluorescent properties of the nanofibre membrane that was blended with CDs were then collected. In addition, in vitro cytotoxicity assessment of the nanofibres were conducted to evaluate the toxicities and biocompatibility.
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