Contact
    Start Publications Highly Sensitive Membrane-Based Pressure Sensors (MePS) for ...
    ←  Publication Finder
    Attension

    Highly Sensitive Membrane-Based Pressure Sensors (MePS) for Real-Time Monitoring of Catalytic Reactions

    Year: 2018

    Journal: Anal. Chem., Volume 90, JUN 19, page 7659–7665

    Authors: Zizzari, Alessandra; Bianco, Monica; del Mercato, Loretta L.; Soraru, Antonio; Carraro, Mauro; Pellegrino, Paolo; Perrone, Elisabetta; Monteduro, Anna G.; Bonchio, Marcella; Rinaldi, Rosaria; Viola, Ilenia; Arima, Valentina

    Organizations: Cluster in Bioimaging (cod. QZYCUMO, "Aiuti a sostegno dei cluster tecnologici regionali 2014", Bando Regione Puglia) [399]; Safe&Smart (PON R&C "Cluster Tecnologici Nazionali") [CTN01_00230_248064]; University of Padova (PRAT) [CPDA158234]

    Functional, flexible, and integrated lab-on-chips, based on elastic membranes, are capable of fine response to external stimuli, so to pave the way for many applications as multiplexed sensors for a wide range of chemical, physical and biomedical processes. Here, we report on the use of elastic thin membranes (TMs), integrated with a reaction chamber, to fabricate a membrane-based pressure sensor (MePS) for reaction monitoring. In particular, the TM becomes the key-element in the design of a highly sensitive MePS capable to monitor gaseous species production in dynamic and temporally fast processes with high resolution and reproducibility. Indeed, we demonstrate the use of a functional MePS integrating a 2 pm thick polydimethylsiloxane TM by monitoring the dioxygen evolution resulting from catalytic hydrogen peroxide dismutation. The operation of the membrane, explained using a diffusion-dominated model, is demonstrated on two similar catalytic systems with catalase-like activity, assembled into polyelectrolyte multilayers capsules. The MePS, tested in a range between 2 and 50 Pa, allows detecting a dioxygen variation of the mu mol L-1 s(-1) order. Due to their structural features, flexibility of integration, and biocompatibility, the MePSs are amenable of future development within advanced lab-on-chips.
    View publication