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    Mastering bioactive coatings of metal oxide nanoparticles and surfaces through phosphonate dendrons

    Year: 2020

    Journal: New J. Chem., Volume 44, FEB 28, page 3206–3214

    Authors: Nguyen, Dinh-Vu; Hugoni, Ludivine; Filippi, Miriam; Perton, Francis; Shi, Da; Voirin, Emilie; Power, Laura; Cotin, Geoffrey; Krafft, Marie-Pierre; Scherberich, Arnaud; Lavalle, Philippe; Begin-Colin, Sylvie; Felder-Flesch, Delphine

    We reported herein an efficient method for constructing dendritic bisphosphonic acid tweezers of generation 1 and 2, which have been proven as versatile surface coatings for metal oxides implants or nanoparticles. These dendritic structures were successfully utilized for different purposes: (i) biocompatible coverings for iron oxide nanoparticles through in vitro assays, (ii) antifouling surface coatings for silica through quartz crystal microbalance studies, and (iii) stabilizing ligands for magnetic nanoparticle-microbubble conjugates via preliminary Langmuir monolayer studies.
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