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    Single-Walled Carbon Nanotube Sensor Platform for the Study of Extracellular Analytes

    Year: 2021

    Journal: ACS Appl. Nano Mater., Volume 4, JAN 22, page 33–42

    Authors: Stapleton, Joseph A.; Hofferber, Eric M.; Meier, Jakob; Ramirez, Ivon Acosta; Iverson, Nicole M.

    Organizations: NIH COBRE grant [P30 GM127200]; National Science Foundation EPSCoRNational Science Foundation (NSF) [OIA-1557417]

    Keywords: nanotechnology; carbon nanotubes; nitric oxide; platform design; extracellular signaling factor detection

    Single-walled carbon nanotubes (SWNT) are attractive targets for the formation of high-density sensor arrays. Their small size and high reactivity could allow for the spatial and temporal study of extracellular products to a degree which greatly surpasses contemporary sensors. However, current methods of SWNT immobilization produce a low fluorescence yield that requires a combination of high magnification, exposure time, and laser intensity to combat, thus limiting the sensor's applications. In this work, a platform for the immobilization of SWNT sensors with increased fluorescence yield, longevity, fluorescence distribution, and fast reaction times is developed.
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