News from Biolin Scientific

Read about the latest from Biolin Scientific, Attension, KSV NIMA, Q-Sense and Sophion


Recorded Webinar Now Online

Posted on May 30, 2017

Professor Fullers webinar Interfacial rheology: From fundamentals to application is now avalaible online.

Sophion in the US is moving to Boston

Posted on May 4, 2017

Great new offices and lab facilities

New Nature paper on QPatch and neuronal stem cells

Posted on April 26, 2017

The QPatch data was done during a 6 weeks stay at Sophion as a part of Denise Franz Pd.D project. Congrats on the publication Denise, hope to see you again soon.

We’re looking for a Service Engineer

Posted on April 11, 2017

Biolin Scientific is looking to fill a part-time position at our New Jersey office,

New address in Shanghai

Posted on March 2, 2017

Our Shanghai office has moved. As of March 1st we have a new adress.

Voltage- and current clamp on induced pluripotent cardiomyocytes with Qube 384

Posted on February 23, 2017

Action potentials are induced in both HL-1 mouse atrial cardiomyocytes and Axiogenesis Cor.4U iPS cell-derived cardiomyocytes.

Get the latest surface action!

Posted on February 2, 2017

A new edition of our newsletter is out.

Cav1.2 on Qube 384

Posted on January 30, 2017

For a long time, screening assays on CaV1.2 have been challenged by the tendency of CaV1.2 cell lines to exhibit declining current levels in the course of the experiment. Here we report a robust assay with high success rates and reliable pharmacology.

• Success rates of 91% for Ca2+ currents and 98% for Ba2+ were achieved
• Stable currents with as low as 0.6 ± 1.8% rundown per minute
• Reference pharmacology in accordance with literature values
• Use-dependent and use-independent mode of action distinguished with different voltage protocols

We’re hiring!

Posted on January 13, 2017

Come join the global Biolin Scientific team. Right now we are looking to fill positions in Finland and Sweden.

Press release

Posted on December 7, 2016

AddLife acquires Biolin Scientific AB – world leading instruments for material analysis at the nanoscale.

TMEM16A – a robust high throughput e-phys assay for a key ion channel involved in cancer and cystic fibrosis

Posted on November 28, 2016

New application report on TMEM16A on Qube with precisely clamped internal Ca2+ and high seal resistances throughout the entire experiment.

Charles River has added a Sophion Qube 384 to their ion channel capabilities

Posted on November 15, 2016

Charles River recently expanded its ion channel capabilities through the addition of a Sophion Qube 384-well automated patch-clamp platform with stacker

Presentations from the Sophion Ion Channel Modulation Symposium 2016 (ICMS)

Posted on November 3, 2016

We are pleased to share with you some of the video presentations from ICMS 2016 in Cambridge this summer.

Q-Sense Dfind – improved analysis software

Posted on October 13, 2016

Biolin Scientific announces today that the company has launched a new, improved version of its QCM-D analysis software.

New scientific method to analyse detergent efficiency published

Posted on September 13, 2016

Biolin Scientific announce today that study results for a new scientific method to evaluate and rank the cleaning ability of new detergent formulations have been published in the journal Tenside Surfactants Detergents (TSD).

Biolin Scientific partners with L.A.B. Analytical to expand analytical instrument business in Scandinavia

Posted on August 22, 2016

Biolin Scientific partners with L.A.B. Analytical. Biolin Scientific has signed an agreement with L.A.B. Analytical, a specialist laboratory appliances provider, to distribute Biolin Scientific’s state-of the-art surface analysis instruments in Sweden, Denmark, Norway and Iceland.

No instrument-to-instrument variation on Sophion Qube384

Posted on May 30, 2016

In electrophysiology literature values for IC50 can range from a few nM to several hundred µM for a specific compound. Variations are caused by many parameters such as the cell line itself, the growth conditions, measurement platform, voltage protocol, solutions etc.

Automatic exchange of intracellular solution on Qube

Posted on May 25, 2016

The flexibility of Qube allows almost indefinite adaptation to user needs. For example, one might want to exchange the intracellular solution (IC) during an experiment. To illustrate this we changed all of the IC during hERG recordings and replenished half the columns with the original solution and the other half with an IC devoid of K+. The left panel shows the hERG current before the IC exchange. The right panel shows the preservation respectively abolishment of the hERG current in alternating columns as a result of exchanging the IC.

Biolin Scientific partner DKSH to expand tensiometer business in China

Posted on May 9, 2016

Biolin Scientific has signed an agreement with DKSH, a leading market expansion services provider with focus on Asia, to market Biolin Scientific’s state-of-the-art tensiometers in China.


First ever giga-seal based high throughput screening of almost 200,000 compounds have been published

Posted on April 1, 2016

The first ever giga-seal based high throughput screening of almost 200,000 compounds have been published using Qube automated patch clamp system.

Biolin Scientific strengthens the Q-Sense product portfolio

Posted on March 16, 2016

Today Biolin Scientific announces a new initiative for Q-SenseTM where the entire product line will be upgraded.

Summer Trainee, Espoo, Finland

Posted on February 1, 2016

Biolin Scientific is looking for a summer trainee for the Analytical Instrument business unit based in Espoo, Finland.

New Book: Quartz Crystal Microbalance – The Principle and Application

Posted on January 25, 2016

 “Quartz Crystal Microbalance – The Principle and Application” is a new book authored by Prof. Guangzhao Zhang and Prof. Guangming Liu published by Sciencepress China.

Christmas gift to UNHCR

Posted on December 16, 2015

This year we choose to give a Christmas gift to UNHCR.
With this donation, UNHCR can help keep refugees warm and safe this winter.

Open Position: Global Product Manager

Posted on November 13, 2015

Biolin Scientific is looking for a Global Product Manager for the Drug Discovery business unit (Sophion brand) based in Ballerup, Copenhagen.

Surface Roughness Corrected Contact Angle – Whitepaper

Posted on November 5, 2015

In this white paper we will take an in-depth look at the principles underlying the 3D Topography Module method, resulting roughness parameters, and also the Wenzel theory used for roughness corrected contact angles. We will also highlight applications and samples that are feasible for this method.

Watch CiPA presentations from this years’ SPS

Posted on October 23, 2015

See the interesting presentations from our CiPA symposium at SPS in Prague

18 new Q-Sensors

Posted on October 6, 2015

Did you know that Q-Sense has 18 new sensor coatings to offer? All used for a wide range of different application areas and as model systems for numerous research problems. Maybe there is one that would really suit your needs?

QCM-D knowledge at NFC Summer School

Posted on September 30, 2015

Last week Application Specialist Jennie Ringberg taught Quartz Crystal Microbalance with Dissipation monitoring, QCM-D, at NFC Summer School in Espoo, Finland.

What’s New in Biomaterials Research?

Posted on August 26, 2015

We recently had the opportunity to interview Abraham Joy, Dept of Polymer Science at the University of Akron, about his research within biomaterials- and biomedical applications.

Biolin Scientific announces new Vice President for the Drug Discovery business unit

Posted on June 22, 2015

Biolin Scientific Holding AB has appointed Thais Johansen as VP of the Drug Discovery business unit (Sophion), where he replaces Morten Sunesen.

OneAttension software update available

Posted on May 26, 2015

Update v2.5 is now available for OneAttension software. The update contains several improvements such as enhancement to dynamic contact angle analysis with Theta optical tensiometers and several usability updates.

Great article by Dr. Sawada involving CiPA assays on QPatch

Posted on May 21, 2015

Please read this really interesting article by Dr. Kohei Sawada involving CiPA assays on QPatch.

BaAMPs -Biofilm-active AMPs database

Posted on May 18, 2015

Check out BaAMPs, the first database dedicated to antimicrobial peptides (AMPs) specifically tested against microbial biofilms.

Amazing Week at Chalmers with Nobel Laureates

Posted on May 6, 2015

This week, some of the most prominent researchers within materials-, energy-, nano- and life science meet at Chalmers in Gothenburg, Sweden for a 5 day workshop symposium called Amazing Week at Chalmers

Biolin Scientific strengthens EMEA sales team

Posted on March 25, 2015

Biolin Scientific is pleased to announce the hiring of Duncan Jarman for the role of Sales Manager EMEA, supporting the Sophion brand of ion channel screening instrumentation

Publication on the use of combined QCM-Ellipsometry

Posted on March 19, 2015

The paper describes the development of a reference biosensor surface, based upon a binary mixture of oligo-ethylene glycol thiols, one of which has biotin at the terminus, adsorbed onto gold as self-assembled monolayers (SAMs).

New Analytical Tool For Enhanced Oil Recovery

Posted on March 10, 2015

Biolin Scientific today announces the launch of the Attension High Pressure Chamber that enables surface analysis at experimental conditions mimicking oil reservoirs. 

Open position: Territory manager South/Central US

Posted on March 5, 2015

Biolin Scientific is seeking a self-motivated Territory Manager to drive sales of its analytical instrument brands; including Q-SENSE brand, the world leader in the Quartz Crystal Microbalance Technology; ATTENSION brand, the best value for measuring contact angles and surface free energy; and KSV-NIMA brands, fine instrumentation for measuring monolayer films

New paper from Merck describing GluK1 uHTS screen

Posted on March 4, 2015

High-Throughput Screen of GluK1 Receptor Identifies Selective Inhibitors with a Variety of Kinetic Profiles Using Fluorescence and Electrophysiology Assays



Watch the webinar on wettability measurements in quality control

Posted on February 20, 2015

Earlier this week we ran a live webinar on wettability measurements in quality control of industrial processes. If you didn’t get the chance to see it, take the opportunity to see the recorded webinar now!

Go to our webinars

Biolin Scientific and Nanion Technologies have entered into a licensing agreement

Posted on February 5, 2015

Stockholm and Munich February 5, 2015 – Biolin Scientific Holding AB, Sweden and Nanion Technologies GmbH, Germany today announce that the parties have entered into a licensing agreement. Biolin Scientific has agreed to grant a non-exclusive license for the key patent related to performing multi-hole, high-throughput ion channel screening to Nanion Technologies in exchange for an undisclosed license fee. The non-exclusive license will provide Nanion Technologies with freedom to operate for the entire life time of the patents.

Biolin Scientific launches new software

Posted on February 3, 2015

Biolin Scientific launches new software that optimizes contact angle measurements for industrial quality control.

Biolin Scientific acquires key patent

Posted on January 27, 2015

Biolin Scientific has acquired a patent from Xention Ltd. that protects multi-hole high-throughput patch clamp analysis. This acquisition strengthens the position of the Sophion brand as the leader in high-throughput ion channel screening using patch clamp technology. 

Common chemicals can alter the saliva’s protective functions

Posted on December 30, 2014

A study at the Institute of Food Research, Norwich UK, has investigated how common chemicals found in toothpaste (Sodium dodecyl sulphate, SDS, and sodium tripolyphosphate, STP) can alter the protective film of the saliva.

Test Your Transformer Oil

Posted on December 9, 2014

All electrical networks depend on the quality of the transformers. Functional failure means maintenance, costly repairs and production down time. The insulating transformer oil in a power transformer says a lot about the transformers condition.

QPatch: Porphyrin derivatives as potent and selective blockers of neuronal Kv1 channels

Posted on December 5, 2014

Dublin City University published a new paper on selective inhibitors of neuronal Kv1 channels.

Selective inhibitors of voltage-activated K+ channels are needed for the treatment of multiple sclerosis. In this work it was discovered that porphyrins bearing 2–4 carbon alkyl ammonium side chains predominantly blocked the Kv1.1 current whilst Kv1.2 was susceptible to a porphyrin bearing polyamine side chains.



How to use QCM-D for biomolecular interactions

Posted on November 17, 2014

Want to learn how to use QCM-D for protein-protein-and nucleic acid/protein interaction studies?

Are you using AFM or Ellipsometry?

Posted on November 13, 2014

Are you looking for a measurement technique that brings a new dimension to what can be analyzed in your lab?

Quantify Your Nanoscale World with QCM-D

Posted on November 4, 2014

Have you heard about QCM-D?

New Application Overview on fabricating nanoparticle thin films

Posted on October 7, 2014

The KSV NIMA Application Overview describes how the Langmuir-Blodgett (LB) technology is used to fabricate highly organized mono- and multi-layer nanoparticle films.


Mimicking Nature’s Expertise in Underwater Adhesives

Posted on September 10, 2014

Marine mussels are unbeatable when it comes to underwater adhesive strategies. They can attach to virtually all inorganic and organic surfaces, tenaciously sustaining their bonds even in saltwater under turbulent wave-swept conditions. 

New Q-Sense Application Note on Surfactant-Surface Interactions

Posted on August 15, 2014

Here is a new application note from Q-Sense on Surfactant-Surface Interactions. This Application Note illustrates how the QCM-D technology can be used to study surfactant interactions with surfaces in real time with nanoscale sensitivity.

New Advances in Dye-Sensitized Solar Cells

Posted on August 6, 2014

Q-Sense, together with Biolin Scientific, has recently co-published a new study titled “Monitoring N3 Dye Adsorption and Desorption on TiO2 Surfaces: A Combined QCM-D and XPS Study”

KSV NIMA Launches a New Langmuir-Blodgett Characterization Kit

Posted on August 5, 2014

KSV NIMA is excited to introduce a new Langmuir-Blodgett characterization kit 

Q-Sense Omega Auto at the 2014 Protein Aggregation Workshop

Posted on August 4, 2014

Biolin Scientific and Q-Sense were sponsors of the recently held 2014 Workshop on Protein Aggregation and Immunogenicity in Breckenridge, Colorado.

The Widest Range of QCM Sensor Coatings Available

Posted on July 30, 2014

Q-Sense offers the widest range of QCM sensor coatings and substrates including metals, metal oxides, polymers, biological sensors and other materials. See below for more details. 

Biolin Scientific and KSV NIMA Return from LB-15

Posted on July 29, 2014

The 15th International Conference on Organized Molecular Films (otherwise known as LB-15) was recently held on Jeju Island in Korea. General topics include studies on Langmuir and Langmuir-Blodgett films, Self-Assembled Monolayers and other nano-scale structures. 

Nature Communication Study Details Gold Nanoparticle/Lipid Bilayer Interactions

Posted on July 25, 2014

A recent paper in Nature Communications elucidates the pathway by which gold nanoparticles spontaneously insert into lipid bilayers. Nature Communications 5, Article number: 4482 doi:10.1038/ncomms5482

A Top University in London Purchases a Q-Sense Omega Auto

Posted on July 17, 2014

A top London-based university has purchased a Q-Sense Omega Auto that will be used for materials characterization. This installation will be a reference site for the Omega Auto and will help facilitate demonstrations, workshops and other events within the UK.

Check out the Omega Auto features and benefits as well as the supported applications and industries

New Application Note for KSV NIMA now available

Posted on July 11, 2014

KSV NIMA has just released a new application note titled: Nanostrand formation of block copolymers at the air/water interface. 

Biolin Scientific Returns from PetroPhase 2014

Posted on June 18, 2014

The 15th annual International Conference on Petroleum Phase Behavior and Fouling just finished up in Houston, TX. 

KSV NIMA Langmuir-Blodgett Training Course

Posted on June 17, 2014

Biolin Scientific Inc. recently held a hands-on training course for the Langmuir and Langmuir-Blodgett technologies and instrumentation in the Linthicum Heights, MD laboratory.

Recorded OneAttension Software Webinars

Posted on June 16, 2014

Learn more about contact angle, surface tension and powder wettability measurements! Watch the OneAttension software webinars that covers how to perform these and many more measurements. You will also see how the new 3D Topography Module is utilized. You find the webinars in the Software section under Attension Services. Go straight to the webinars.


Q-Sense Amine Coupling Sensor

Posted on June 4, 2014

We hope you haven’t missed that we recently launched a new Q-Sense sensor? This functionalized sensor complements our existing range of bio-surfaces; Q-Sense Biotin Sensor and Q-Sense His-tag Capturing Sensor. With the Amine coupling sensor added to our product range, we now offer an expanded set of functionalities, targeting different protein immobilization strategies which enables additional applications with Q-Sense QCM-D instruments.

Into graphene and nanoparticles?

Posted on May 26, 2014

Check out 10 of the latest and most influential publications with KSV NIMA Langmuir-Blodgett Troughs in graphene and nanoparticle research! We have gathered them for you with a brief summary and if you want to read more, click on the title.

First deals for high-speed screening of ion channel drug targets

Posted on May 19, 2014

Sophion Bioscience (, part of Biolin Scientific, has received its first purchase orders for its new high throughput screening platform from leading pharma companies


Posted on May 14, 2014

丹麦巴勒鲁普2014年5月14日电  瑞典百欧林科技有限公司 (Biolin Scientific) 旗下子公司 Sophion Bioscience ( ) 已经获得领先制药公司采购其最新高通量筛选平台的首批订单。该 Sophion Qube™ 平台直接测量潜在新候选药物对活细胞离子通道的作用功效。通过将高质量记录和高通量相结合,Sophion Qube可以显著提高离子通道药物发现初始阶段的效率。

Sophion becomes a Gazelle business

Posted on March 7, 2014

Since 1995 the Danish financial newspaper Børsen has identified the Danish growth elite, and each year nominated a number of growth companies that fulfill the criteria.

New Application Note on Polymers

Posted on March 7, 2014

New Application Note available on the characterization of polymer layer swelling and collapse by the QCM-D technology.

Nobel Prize in Physiology or Medicine 2013

Posted on February 12, 2014

The Nobel Prize in Physiology or Medicine 2013 was awarded jointly to James E. Rothman, Randy W. Schekman and Thomas C. Südhof “for their discoveries of machinery regulating vesicle traffic, a major transport system in our cells”.

KSV NIMA Stand-Alone MicroBAM

Posted on February 10, 2014

The KSV NIMA Brewster Angle Microscopes represents the latest in BAM instrumentation allowing high resolution and fully focused real-time imaging of monolayers.

Rechanneling the Current Cardiac Safety Paradigm

Posted on July 23, 2013

The recent Think Tank Meeting held at the FDA “Rechanneling the Current Cardiac Safety Paradigm” (23rd of July, 2013) concluded:  A robust and biologically relevant assessment of potential clinical arrhythmia should include assessment of multiple ion channels and the current s7b minimal standard does not reflect this.

Click here for more information.