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QSense QCM-D - See molecular interactions at surfaces and interfaces in real time

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Move beyond endpoint observations and understand the interfacial dynamics that shape products and processes.

By tracking changes in mass and viscoelastic properties, QSense reveals how material is taken up, reorganized and removed at the surface or interface. This helps you connect interfacial behaviour to the outcomes that matter in your scientific, development and application work.

 

QSense in action

Interested in working with our QSense instruments in your lab? Watch the video to see our instruments in action. 

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Why surfaces and interfaces matter

Outcomes can be shaped where materials meet

Across products and processes, whether things work as intended or fail can depend on what happens at surfaces and interfaces.

A cleaning step may remove a soil layer  or leave residues behind. A membrane may keep its flow — or foul and lose performance. A formulation may remain stable — or interact with a surface in ways that cause loss or incompatibility. A battery may remain safe and long-lived — or degrade through unstable interfaces and dendrite growth.

In each case, the visible outcome can depend on dynamic interfacial processes that are not always apparent from conventional bulk, endpoint or before-and-after measurements.

What is EQCM-D-1

The hidden layer behind visible outcomes

See the dynamics in between

At surfaces and interfaces, molecules, particles and films can adsorb, desorb, bind, release, build up, degrade, swell, collapse, foul, reorganize or be removed.

These processes may be small in scale, but they can have a large effect on the outcomes you care about: stability, fouling, cleaning efficiency, material compatibility, biocompatibility, battery lifetime, process efficiency and more.

When interfacial processes go unnoticed, you may see the outcome without understanding the cause. To design and improve these systems, you need insight into what happens at surfaces and interfaces as the process unfolds.

QCM-D

QSense QCM-D is a surface-sensitive, label-free technology that enables you to follow molecule–surface and interfacial processes in real time at the nanoscale.

 

Not sure which QCM-D instrument you need?

Try the Instrument Selector

 

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A complete solution for surface and interface analysis

QSense is more than an instrument. The complete solution includes sensors, software, service and application support to help you generate reliable data and extract the insight you need.

Sensors for relevant surfaces
QSense sensors are available in a broad range of materials and coatings, with customization options to help mimic the surfaces that matter in your system.

Software for data analysis
QSense software supports the workflow from data collection to analysis and reporting, helping you extract information such as mass, thickness, viscoelastic properties and adsorption rates.

Application support and service
Our application specialists and service engineers help you plan experiments, interpret results, troubleshoot and keep your system performing reliably.

Sensors

Sensors

We have the widest range of quality sensors on the market, and we can customize both materials and coatings based on your wishes. Explore our sensors

What our customers say

Our instruments are present at many prestigious universities and research facilities world wide. Take a minute to find out what others say working with QSense instruments. 

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Prof. Nam-Joon Cho, School of Materials Science and Engineering, Nanyang Technological University, Singapore

"QCM-D technology is a key part of our biointerfacial science research that spans fundamental biomacromolecular investigations to applied studies involving antiviral drug development. The QSense instruments, which we have used for nearly two decades, are robust and can track complex biological phenomena in real-time and with label-free readouts that have helped us to deeply characterize a wide range of systems related to proteins and lipid membranes. Together with our analytical modeling efforts, there is a really bright future to continue applying QCM-D technology in new directions across many important scientific disciplines."

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Joshua A. Jackman, Assistant Professor, Sungkyunkwan University, South Korea

"Using QSense measurement tools, our lab has investigated many very interesting protein and lipid systems in aqueous and non-aqueous environments and the QCM-D measurement capabilities have proven critical to study molecular-level interaction behaviors at solid-liquid interfaces. One of the most exciting examples has involved antimicrobial lipids, in which case the QCM-D technique has proven extremely useful to distinguish the mechanisms of action of different compounds interacting with membrane-mimicking supported lipid bilayers. Such mechanistic distinctions were seen for the first time by the QCM-D technique, demonstrating its potential to complement and in some cases surpass the analytical capabilities of traditional biological assays. Looking forward, we see enormous potential to translate fundamental insights obtained from QCM-D measurements into numerous applications across the healthcare, biotechnology, and agricultural spaces among various opportunities."