- You want ease of use
Get up and running with this out-of-the-box solution. Everything you need to get started is included - You want flexibility
Build the system to suit your needs,
now and in the future - You want automation
Minimize hands-on time and maximize reproducibility - You value working with the best
Trust the results you get from the next-generation premium QCM-D instrument
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- QSense
- QCM-D Instruments
- QSense Omni
QCM-D
QSense Omni
QSense Omni gives you sharper QCM-D data and a smooth journey in the lab. Unfold unique insights quicker and base your decisions on reliable results from highly controlled measurements.

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Widen your view
This 3-minute video will give you a quick view of QSense Omni capabilities. Watch the video in fullscreen for the best experience.
Technical Features
- Automatic sample handling
- Automatic quality control
- Direct injection fluidics
- Liquid exchange
- Automatic sensor locking
- Integrated sample heating
- Flexible flow rate between channels
- Live script editing
3 reasons to invest
Easier data interpretation
Through leading signal processing and a fast and reproducible liquid exchange, QSense Omni gives you sharper and more concise data. For easier and more confident data interpretation and analysis.
Smooth journey
Running successful QCM-D experiments with trustworthy and reproducible results has never been easier. Thanks to intuitive design, smart workflows and clever automation, productivity will increase, and you can spend your working-day more efficiently.
Grow with your research
With bold design and smart functions, QSense Omni is made for scientific progress and future innovation. By upgrading to more channels, or adding QSense Orbit for complementary measurements, you can go beyond entry capabilities, and grow with your research.
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Measurement range and capacity
Measurement channels | 1 - 4 |
Working temperature | 4 to 70 °C |
Sensors (frequency range) | 5 MHz (1-72) |
Number of measured harmonics | 7, allows for full viscoelastic modeling |
Sample and fluidics
Volume above sensor | ~ 20 μl |
Minimum sample volume | ~ 90 μl |
Flow rates | Typical flow rate 20 μl/min. Flow speed range 1-200 μl/min |
Performance characteristics
Maximum time resolution | 300 data points per second (each data point represents an f and D value) |
LOD (3 x noise) |
0.24 See the graph below |
Minimum noise | Frequency: 0.0045 Hz Mass: 0.08 ng/cm2 Dissipation: 1∙10-9 |
Long-term stability* | Frequency: < 0.25 Hz/h Dissipation: < 0.04.10-6 /h Temperature: < 0.003˚C |
All specifications are subject to change without prior notice
* The temperature stability depends on variations in how the ambient affects the warming or cooling of the chamber. The specified temperature stability may not be reached if the room temperature changes more than ± 1° C, due to draft or heat source for example.
Values taken after 1 h measurement with a QSX 303 SiO sensor in DI water at 25° C, Flow 20 μl/min and a data rate of 1 datapoint/s. Data interval used for analysis: 2 min. Even better stability can be achieved by waiting longer than 1 hour. Weight excluding external power supply.
Optimal real-life performance
Applying a higher sample rate inevitably leads to higher noise and compromised limit of detection (LOD).
With significantly improved noise level, QSense Omni offers improved Limit of Detection. The figure and table below
describe the Limit of Detection of QSense Omni at three different sampling intervals, and demonstrates the low limit
of detection achieved also at high sample rates.
The below figure and table describe speed and limit of detection (LOD) per acquisition mode.
Speed and limit of detection (LOD) per acquisition mode. Theoretical limit of Detection (LOD) at different sample intervals. Limit of detection is set to 3 times frequency noise level.
Performance characteristics. Measurements were performed with QSX 303 SiO sensors at 20°C temperature, and in deionized water at flow of 15μL/min, using one measurement channel. Each measurement mode was measured for approximately 5 minutes, and standard deviation of data points was collected within a set time range of 1 min to statistically determine noise data.
QSoft and Dfind software
Discover QSoft Omni software - a new, user-friendly software designed to
guide you through experiment set-up and produce successful results. While you prepare your experiment the QSoft Omni software continuously makes quality controls in the background to ensure optimal conditions for your measurement. QSoft Omni is collecting your data whereas Dfind makes your analysis easier.
QSoft Omni features
- Guided workflow takes you
through experiment set-up - Automated quality checks in the
background helps ensure optimal
experiment outcome - Drag and drop interface and live
script editing makes it easy to
develop scripts - Event log featuring both
automated actions and user
annotation
Computer requirements
- USB 2.0 or higher with type A connector
- Intel Core i5 processor (or equivalent)
- 8 GB of RAM or better
- > 1920 x 1080 px screen resolutions
- Windows 10 or later
Add more possibilities
Have a look at a selection of available add-ons compatible with QSense Omni to expand your experimental set up and possibilities.
Electrochemistry Module
Want to conduct simultaneous QCM-D and electrochemistry measurements on the same surface? This module supports a wide range of electrochemical methods, for instance cyclic voltammetry and electrochemical impedance measurements to explore polymer behavior, electrostatic interactions, corrosion, etc.
Window Module
Giving optical access to the sensor surface, this module enables simultaneous QCM-D and microscopy measurements on the same surface. You can also perform light or irradiation sensitive measurements.
Open Module
The Open module is tubeless with the lowest possible sample volume requirement. You can directly pipette a minimal amount of liquid to cover the sensor. This module will provide for evaporation studies, external triggered reactions such as photo induced reaction and chemically triggered reactions.
Humidity Module
Designed to enable measurements of vapor uptake and release from thin films coated
on the sensor.
What our beta testers say
Peter Stengel, BASF SE
“I observed reduced cross-contamination, which is crucial for obtaining accurate data. I recognize the potential and value of this in our
future studies”
Franziska Tauber, BASF SE
“From my initial experience conducting the experiment, it became evident that it was designed with ease-of-use in mind, making it accessible to multiple users at the same time with no difficulties”
Learn more
We have gathered all our in-depth knowledge associated with QSense Pro. Browse around amongst guides, overviews and white papers to find a topic of interest.
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How to Characterize Lipid-Based Systems with QCM-D
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QSense Cleaning Profile
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QCM-D vs other QCMs
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The Sauerbrey Relation
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QCM-D Data Analysis
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QCM-D Studies of Engineered Nanoparticles
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Analytical Methods to Characterize Lipid-based Systems
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Development of a New Method for the Formation of SLBs on Solid Support using QSense QCM-D
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Determining Cleansing Efficacy of Elfan AT 84 using a QCM-D Assay
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Analyzing Cleaning of Hard Surfaces with QSense
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QSense Etching Guide
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QCM-D in Research
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Key Publications on the Formation of Supported Lipid Bilayers
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QCM-D vs SPR
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The Working Principles of QCM and QCM-D
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What is Dissipation?
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Temperature Stability in QCM Measurements
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How to Generate Quality QCM-D Data
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How QCM Results are Influenced by Layer Distribution
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What is Piezoelectricity?
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QCM-D vs other QCMs
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How to Optimize the QCM-D Baseline Stability
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Characterization of Polymer-based Systems
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QCM-D in Drug Formulation and Storage
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Analysis of Surfactant-Surface Interactions with QSense
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What is a Viscoelastic material?
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Characterization of Biomolecular Interactions
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Dfind Basic Training Course
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Basics of QCM-D
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How do we Stop the Next Pandemic from an Unknown Virus?
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Surface Science – a Field Rich in Science and Applications
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QCM-D Analysis in Virus-related Research
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Biomaterials – Man-made Materials for Regenerative Medicine
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QCM-D as a Tool to Study the Binding of Viruses
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Nanocellulose Research with QCM-D
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Using QCM-D in the Food Industry
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Characterization of Surfaces and Surface Reactions in Energy Storage
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How Excipients, Surfaces and Formulation Conditions Affect Therapeutic Proteins
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What is Biocompatibility?
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The Dissipation Factor in QCM-D Technology
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Why it is Useful to use Multiple Overtones in QCM Measurements?
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QSense Analysis in CMP
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Why the Resonance Frequency of a QCM Sensor is 5MHz
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Analyze Surface-induced Complement Activation
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Analyzing Vapor Uptake and Release with QCM-D
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Monitoring of Polyelectrolyte Multilayer Build-up and Crosslinking using QCM-D
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Screening Nanoparticle - Protein Interactions
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QCM-D as a Screening Tool for Protein Adsorption
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Characterization of Polymer Layer Swelling, Crosslinking and Collapse
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Adsorption and Aggregation of Monoclonal Antibodies at Silicone Oil-Water Interfaces
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QCM-D Publications in Battery Research
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Biomembrane Models and Interactions Therein
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Getting Started with QSense Dfind
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Data Modeling in QSense Dfind
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QCM-D Characterization of Antimicrobial Lipid Interactions with Supported Lipid Bilayers: Towards Antiviral Applications in the Biomedical and Agricultural Sectors
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Implementing quartz crystal microbalance with dissipation monitoring for the development of novel biosensing assays
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EQCM-D Analysis in Battery Development
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