QCM-D

QSense Omni

QSense Omni gives you sharper QCM-D data and a smooth journey in the lab. Unfold unique insights quicker and base your decisions on reliable results from highly controlled measurements.

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Guide

Most suitable when

You want ease of use
Get up and running with this out-of-the-box solution. Everything you need to get started is included
You want flexibility
Build the system to suit your needs,
now and in the future
You want automation
Minimize hands-on time and maximize reproducibility
You value working with the best
Trust the results you get from the next-generation premium QCM-D instrument

Widen your view

This 3-minute video will give you a quick view of QSense Omni capabilities. Watch the video in fullscreen for the best experience.

Technical Features

Automatic sample handling
Automatic quality control
Direct injection fluidics
Liquid exchange
Automatic sensor locking
Integrated sample heating
Flexible flow rate between channels
Live script editing

3 reasons to invest

Easier data interpretation

Through leading signal processing and a fast and reproducible liquid exchange, QSense Omni gives you sharper and more concise data. For easier and more confident data interpretation and analysis.

Smooth journey

Running successful QCM-D experiments with trustworthy and reproducible results has never been easier. Thanks to intuitive design, smart workflows and clever automation, productivity will increase, and you can spend your working-day more efficiently.

Grow with your research

With bold design and smart functions, QSense Omni is made for scientific progress and future innovation. By upgrading to more channels, or adding QSense Orbit for complementary measurements, you can go beyond entry capabilities, and grow with your research.

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A closer look

Let's dive into the specifications of QSense Omni. You can also compare the data to other QSense instruments to find what you are looking for.

Measurement range and capacity

Measurement channels	1 - 4
Working temperature	4 to 70 °C
Sensors (frequency range)	5 MHz (1-72)
Number of measured harmonics	7, allows for full viscoelastic modeling

Sample and fluidics

Volume above sensor	~ 20 μl
Minimum sample volume	~ 90 μl
Flow rates	Typical flow rate 20 μl/min. Flow speed range 1-200 μl/min

Performance characteristics

Maximum time resolution	300 data points per second (each data point represents an f and D value)
LOD (3 x noise)	0.24 See the graph below
Minimum noise	Frequency: 0.0045 Hz Mass: 0.08 ng/cm2 Dissipation: 1∙10-9
Long-term stability*	Frequency: < 0.25 Hz/h Dissipation: < 0.04.10-6 /h Temperature: < 0.003˚C

All specifications are subject to change without prior notice

* The temperature stability depends on variations in how the ambient affects the warming or cooling of the chamber. The specified temperature stability may not be reached if the room temperature changes more than ± 1° C, due to draft or heat source for example.
Values taken after 1 h measurement with a QSX 303 SiO sensor in DI water at 25° C, Flow 20 μl/min and a data rate of 1 datapoint/s. Data interval used for analysis: 2 min. Even better stability can be achieved by waiting longer than 1 hour. Weight excluding external power supply.

Optimal real-life performance

Applying a higher sample rate inevitably leads to higher noise and compromised limit of detection (LOD).
With significantly improved noise level, QSense Omni offers improved Limit of Detection. The figure and table below
describe the Limit of Detection of QSense Omni at three different sampling intervals, and demonstrates the low limit
of detection achieved also at high sample rates.

The below figure and table describe speed and limit of detection (LOD) per acquisition mode.

Speed and limit of detection (LOD) per acquisition mode. Theoretical limit of Detection (LOD) at different sample intervals. Limit of detection is set to 3 times frequency noise level.

Data Capture Performance characteristics. Measurements were performed with QSX 303 SiO sensors at 20°C temperature, and in deionized water at flow of 15μL/min, using one measurement channel. Each measurement mode was measured for approximately 5 minutes, and standard deviation of data points was collected within a set time range of 1 min to statistically determine noise data.

Standard sensors

The sensor is at the heart of the QCM-D experiment. Browse the widest range of sensors on the market to find out which sensor material and coating is best suited for your research.

We offer over 50 standard sensors - from various metals, oxides and carbides to polymers, functionalized coatings and and standardized soils. Our sensors are developed and produced to provide you with stable, reliable and reproducible data. Full performance is ensured through extensive quality controls and guaranteed for one-time use according to the recommendations.

Customized sensors

Sensor materials and coatings based on your specific needs

Top suggestions

Stainless Steel SS2343

QSX 305

PS-Hydrophobic Polystyrene

See all sensors

QSoft and Dfind software

Discover QSoft Omni software - a new, user-friendly software designed to
guide you through experiment set-up and produce successful results. While you prepare your experiment the QSoft Omni software continuously makes quality controls in the background to ensure optimal conditions for your measurement. QSoft Omni is collecting your data whereas Dfind makes your analysis easier.

QSoft Omni features

Guided workflow takes you
through experiment set-up
Automated quality checks in the
background helps ensure optimal
experiment outcome
Drag and drop interface and live
script editing makes it easy to
develop scripts
Event log featuring both
automated actions and user
annotation

Would you like to know more about the details of Dfind and learn how the subscription works?

Computer requirements

USB 2.0 or higher with type A connector
Intel Core i5 processor (or equivalent)
8 GB of RAM or better

> 1920 x 1080 px screen resolutions
Windows 10 or later

Add more possibilities

Have a look at a selection of available add-ons compatible with QSense Omni to expand your experimental set up and possibilities.

Electrochemistry Module

Want to conduct simultaneous QCM-D and electrochemistry measurements on the same surface? This module supports a wide range of electrochemical methods, for instance cyclic voltammetry and electrochemical impedance measurements to explore polymer behavior, electrostatic interactions, corrosion, etc.

Window Module

Giving optical access to the sensor surface, this module enables simultaneous QCM-D and microscopy measurements on the same surface. You can also perform light or irradiation sensitive measurements.

Open Module

The Open module is tubeless with the lowest possible sample volume requirement. You can directly pipette a minimal amount of liquid to cover the sensor. This module will provide for evaporation studies, external triggered reactions such as photo induced reaction and chemically triggered reactions.

Humidity Module

Designed to enable measurements of vapor uptake and release from thin films coated
on the sensor.

Configure QSense Omni with accessories & modules in our Instrument Selector!

What our beta testers say

Peter Stengel, BASF SE

“I observed reduced cross-contamination, which is crucial for obtaining accurate data. I recognize the potential and value of this in our
future studies”

Franziska Tauber, BASF SE

“From my initial experience conducting the experiment, it became evident that it was designed with ease-of-use in mind, making it accessible to multiple users at the same time with no difficulties”

Learn more

We have gathered all our in-depth knowledge associated with QSense Pro. Browse around amongst guides, overviews and white papers to find a topic of interest.

QSense

Guide

How to read a QCM Specification

There are key parameters to keep an eye on when investing in a new QCM instrument. Learn what they mean, and why they are important.

Download

QSense

Overview

Information Obtained with QSense QCM-D

We have summarized the parameters and processes that can be studied with QCM-D for you.

Biolin Scientific China

German Webshop

Most suitable when

Widen your view

Technical Features

3 reasons to invest

Easier data interpretation

Smooth journey

Grow with your research

A closer look

Measurement range and capacity

Sample and fluidics

Performance characteristics

Optimal real-life performance

Top suggestions

See all sensors

QSoft and Dfind software

QSoft Omni features

Computer requirements

Add more possibilities

Electrochemistry Module

Window Module

Open Module

Humidity Module

What our beta testers say

Peter Stengel, BASF SE

Franziska Tauber, BASF SE

Learn more

How to read a QCM Specification

Information Obtained with QSense QCM-D

How to Characterize Lipid-Based Systems with QCM-D

QSense Cleaning Profile

QCM-D vs other QCMs

The Sauerbrey Relation

QCM-D Data Analysis

QCM-D Studies of Engineered Nanoparticles

Analytical Methods to Characterize Lipid-based Systems

Development of a New Method for the Formation of SLBs on Solid Support using QSense QCM-D

Determining Cleansing Efficacy of Elfan AT 84 using a QCM-D Assay

Analyzing Cleaning of Hard Surfaces with QSense

QSense Etching Guide

QCM-D in Research

Key Publications on the Formation of Supported Lipid Bilayers

QCM-D vs SPR

The Working Principles of QCM and QCM-D

What is Dissipation?

Temperature Stability in QCM Measurements

How to Generate Quality QCM-D Data

How QCM Results are Influenced by Layer Distribution

What is Piezoelectricity?

QCM-D vs other QCMs

How to Optimize the QCM-D Baseline Stability

Characterization of Polymer-based Systems

QCM-D in Drug Formulation and Storage

Analysis of Surfactant-Surface Interactions with QSense

What is a Viscoelastic material?

Characterization of Biomolecular Interactions

Dfind Basic Training Course

Basics of QCM-D

How do we Stop the Next Pandemic from an Unknown Virus?

Surface Science – a Field Rich in Science and Applications

QCM-D Analysis in Virus-related Research

Biomaterials – Man-made Materials for Regenerative Medicine

QCM-D as a Tool to Study the Binding of Viruses

Nanocellulose Research with QCM-D

Using QCM-D in the Food Industry

Characterization of Surfaces and Surface Reactions in Energy Storage

How Excipients, Surfaces and Formulation Conditions Affect Therapeutic Proteins

What is Biocompatibility?

The Dissipation Factor in QCM-D Technology

Why it is Useful to use Multiple Overtones in QCM Measurements?

QSense Analysis in CMP

Why the Resonance Frequency of a QCM Sensor is 5MHz

Analyze Surface-induced Complement Activation

Analyzing Vapor Uptake and Release with QCM-D

Monitoring of Polyelectrolyte Multilayer Build-up and Crosslinking using QCM-D

Screening Nanoparticle - Protein Interactions

QCM-D as a Screening Tool for Protein Adsorption

Characterization of Polymer Layer Swelling, Crosslinking and Collapse

Adsorption and Aggregation of Monoclonal Antibodies at Silicone Oil-Water Interfaces