In a hurry?

Discover QSense Omni  and all of its advantages in this 2 minutes long video.
Omni QSense 4th generation QCM-D platform

Phenomena

  • Adsorption
  • Desorption
  • Binding and interactions
  • Swelling
  • De-swelling, crosslinking and collapse
  • Degradation, corrosion and etching

Up to 4 automated measurement channels

Apply same or different scripts simultaneously
Upgradable

Key features

  • Measure mass, thickness, and viscoelastic properties of rigid and soft films

    7-harmonic QCM-D with unique QSense Decay technology enables qualitative and quantitative analysis

  • Best limit of detection and sharpest QCM-D data

    4 times lower noise level and better limit of detection than any other QCM-D instrument

  • Automated quality controlled measurements

    Save time and perform reproducible measurements with temperature controlled chamber

  • Up to 4 individual measurement channels

    Measure in parallel using same or different scripts, flow rates and temperatures

  • The broadest offer of sensor surfaces and coatings

    Set up model systems as close as possible to real-world conditions

  • Develop and refine scripts with Live script editing

    Adjust your scripts while running the experiment
Complete analysis set-up

Intuitive Software for Effortless Experimentation

As you set up your experiment, QSoft Omni software runs continuous quality controls in the background to guarantee ideal conditions for your measurement. While QSoft Omni gathers your data, Dfind simplifies your analysis process.

analyzer (1)

Measurement conditions

  • Flow mode
  • Stagnant mode
  • Gas phase Requires add-on
  • Liquid phase
  • Harsh chemicals
  • Low temperature
  • High viscosity
  • Inert surface Requires add-on

A closer look

Let's dive into the specifications of QSense Omni. You can also compare the data to other QSense instruments to find what you are looking for.

Measurement range and capacity

Measurement channels 1 - 4 
Working temperature 4 to 70 °C
Sensors (frequency range) 5 MHz (1-72)
Number of measured harmonics 7, allows for full viscoelastic modeling


Sample and fluidics 

 Volume above sensor     ~ 20 μl
Minimum sample volume ~ 90 μl
Flow rates Typical flow rate 20 μl/min. Flow speed range 1-200 μl/min

Performance characteristics 

Maximum time resolution 300 data points per second (each data point represents an f and D value)
   LOD (3 x noise)

   0.24 ng/cm2

   See the graph below
Minimum noise Frequency: 0.0045 Hz
Mass: 0.08 ng/cm2
Dissipation: 1∙10-9
Long-term stability* Frequency: < 0.25 Hz/h
Dissipation: < 0.04.10-6 /h
Temperature: < 0.003˚C

All specifications are subject to change without prior notice

* The temperature stability depends on variations in how the ambient affects the warming or cooling of the chamber. The specified temperature stability may not be reached if the room temperature changes more than ± 1° C, due to draft or heat source for example.
Values taken after 1 h measurement with a QSX 303 SiO sensor in DI water at 25° C, Flow 20 μl/min and a data rate of 1 datapoint/s. Data interval used for analysis: 2 min. Even better stability can be achieved by waiting longer than 1 hour.  Weight excluding external power supply.

Optimal real-life performance

Applying a higher sample rate inevitably leads to higher noise and compromised limit of detection (LOD).
With significantly improved noise level, QSense Omni offers improved Limit of Detection. The figure and table below
describe the Limit of Detection of QSense Omni at three different sampling intervals, and demonstrates the low limit
of detection achieved also at high sample rates.

The below figure and table describe speed and limit of detection (LOD) per acquisition mode.

LOD updated by jennie cropped

Speed and limit of detection (LOD) per acquisition mode. Theoretical limit of Detection (LOD) at different sample intervals. Limit of detection is set to 3 times frequency noise level.

Data CapturePerformance characteristics. Measurements were performed with QSX 303 SiO sensors at 20°C temperature, and in deionized water at flow of 15μL/min, using one measurement channel. Each measurement mode was measured for approximately 5 minutes, and standard deviation of data points was collected within a set time range of 1 min to statistically determine noise data.
Standard sensors
The sensor is at the heart of the QCM-D experiment. Browse the widest range of sensors on the market to find out which sensor material and coating is best suited for your research.
We offer over 50 standard sensors - from various metals, oxides and carbides to polymers, functionalized coatings and and standardized soils. Our sensors are developed and produced to provide you with stable, reliable and reproducible data. Full performance is ensured through extensive quality controls and guaranteed for one-time use according to the recommendations.
Customized sensors
Sensor materials and coatings based on your specific needs

Top suggestions

Gold-Sensor
QSX 301
Gold
Silica-Sensor
QSX 303
Silicon Dioxide
Stainless-steel-sensor
QSX 304
Stainless Steel SS2343
Gold-Sensor
QSX 305
PS-Hydrophobic Polystyrene

See all sensors

Explore our sensors

QSoft and Dfind software

Discover QSoft Omni software - a new, user-friendly software designed to
guide you through experiment set-up and produce successful results. While you prepare your experiment the QSoft Omni software continuously makes quality controls in the background to ensure optimal conditions for your measurement. QSoft Omni is collecting your data whereas Dfind makes your analysis easier. 

QSoft Omni features

  • Guided workflow takes you
    through experiment set-up
  • Automated quality checks in the
    background helps ensure optimal
    experiment outcome
  • Drag and drop interface and live
    script editing makes it easy to
    develop scripts
  • Event log featuring both
    automated actions and user
    annotation
Would you like to know more about the details of Dfind and learn how the subscription works?

Learn more about Dfind!

Computer requirements

 
  • USB 2.0 or higher with type A connector
  • Intel Core i5 processor (or equivalent)
  • 8 GB of RAM or better


 
  • > 1920 x 1080 px screen resolutions
  • Windows 10 or later

 

Add more possibilities

Have a look at a selection of available add-ons compatible with QSense Omni to expand your experimental set up and possibilities.

Electrochemistry-module-qem-401

Electrochemistry Module

Want to conduct simultaneous QCM-D and electrochemistry measurements on the same surface? This module supports a wide range of electrochemical methods, for instance cyclic voltammetry and electrochemical impedance measurements to explore polymer behavior, electrostatic interactions, corrosion, etc.

Read more

qsense-window-module

Window Module

Giving optical access to the sensor surface, this module enables simultaneous QCM-D and microscopy measurements on the same surface. You can also perform light or irradiation sensitive measurements.

Read more

qsense-open-module

Open Module

The Open module is tubeless with the lowest possible sample volume requirement. You can directly pipette a minimal amount of liquid to cover the sensor. This module will provide for evaporation studies, external triggered reactions such as photo induced reaction and chemically triggered reactions.

Read more

Humidity-module-qhm-401

Humidity Module

Designed to enable measurements of vapor uptake and release from thin films coated
on the sensor.

Read more

What our beta testers say

Peter Stengel, BASF SE

“I observed reduced cross-contamination, which is crucial for obtaining accurate data. I recognize the potential and value of this in our
future studies”

Franziska Tauber, BASF SE

“From my initial experience conducting the experiment, it became evident that it was designed with ease-of-use in mind, making it accessible to multiple users at the same time with no difficulties”

Learn more

We have gathered all our in-depth knowledge associated with Omni. Browse around amongst guides, overviews and white papers to find a topic of interest. 

  • QSense
How Excipients, Surfaces and Formulation Conditions Affect Therapeutic Proteins
Webinar

How Excipients, Surfaces and Formulation Conditions Affect Therapeutic Proteins

Can QCM-D quantify how surfactants affect protein-surface interaction? Watch this webinar with Dr. Archana Jaiswal to find out more.

Go there
  • QSense
Basics of QCM-D
Webinar

Basics of QCM-D

Learn the fundamentals of the technology, its possibilities and limitations and get a deeper understanding of nanometer layers.

Go there
  • QSense
How to Optimize the QCM-D Baseline Stability
Guide

How to Optimize the QCM-D Baseline Stability

9 steps to eliminate error sources and optimize reproducibility

Download
  • QSense
The Working Principles of QCM and QCM-D
Overview

The Working Principles of QCM and QCM-D

Learn the fundamentals of how the technologies work, and what is the difference between them.

Get it
  • QSense
QCM-D in Drug Formulation and Storage
Case Study

QCM-D in Drug Formulation and Storage

Analyze and quantify protein adsorption to surfaces.

Get it
  • QSense
QCM-D vs SPR
Overview

QCM-D vs SPR

Learn more about the differences between the two methods to find out which you should use.

Get it
  • QSense
QCM-D vs other QCMs
Overview

QCM-D vs other QCMs

Let this brief overview guide you to your most suitable choice of QCM.

Get it
  • QSense
What is Piezoelectricity?
Overview

What is Piezoelectricity?

Bone, wood and quartz are all piezoelectric materials. Learn about piezoelectricity and how it works

Get it
  • QSense
How QCM Results are Influenced by Layer Distribution
Overview

How QCM Results are Influenced by Layer Distribution

The distribution of the measured layer is key to your results. Discover why and how to handle it.

Get it
  • QSense
Why the Resonance Frequency of a QCM Sensor is 5MHz
Overview

Why the Resonance Frequency of a QCM Sensor is 5MHz

What determines the value of the fundamental resonance frequency? In this overview, we explain the theory behind the number.

Get it
  • QSense
Characterization of Polymer-based Systems
Overview

Characterization of Polymer-based Systems

Analyze layer build-up, conformation and molecular interaction with QSense QCM-D

Get it
  • QSense
Using QCM-D in the Food Industry
Webinar

Using QCM-D in the Food Industry

Learn more about QCM-D in food industry with studies of shelf life from Cornell University.

Go there
  • QSense
What is Biocompatibility?
Overview

What is Biocompatibility?

In this overview we explain how biocompatibility is defined and give examples of what the property entails.

Get it
  • QSense
Why it is Useful to use Multiple Overtones in QCM Measurements?
Overview

Why it is Useful to use Multiple Overtones in QCM Measurements?

Learn what information the overtones offer in this overview.

Get it
  • QSense
Nanocellulose Research with QCM-D
Webinar

Nanocellulose Research with QCM-D

Watch our webinar on Nanocellulose Research with QCM-D where we will discuss thin films of cellulose nanofibrils development, and their characterization. 

Go there
  • QSense
Analysis of Surfactant-Surface Interactions with QSense
Case Study

Analysis of Surfactant-Surface Interactions with QSense

Find out how to analyze surfactant interaction with surfaces at the nanoscale.

Get it
  • QSense
Getting Started with QSense Dfind
Webinar

Getting Started with QSense Dfind

QSense Dfind assists you with raw data review, modeling, information extraction and generating reports. Get started with the webinar by Patricia Passanesi, Application Scientist at Biolin Scientific

Go there
  • QSense
Data Modeling in QSense Dfind
Webinar

Data Modeling in QSense Dfind

Check out the webinar by Fredrik Pettersson on physical modeling using QSense Dfind.

Go there
  • QSense
QCM-D as a Screening Tool for Protein Adsorption
Case Study

QCM-D as a Screening Tool for Protein Adsorption

Proteins tend to passively adsorb to surfaces via hydrophobic interactions. In this application note we show how protein adsorption can be characterized with QCM-D.

Get it
  • QSense
Analyzing Vapor Uptake and Release with QCM-D
Case Study

Analyzing Vapor Uptake and Release with QCM-D

Read about how QCM-D can be used to analyse how water uptake and release affects film thickness

Get it
  • QSense
Surface Science – a Field Rich in Science and Applications
Webinar

Surface Science – a Field Rich in Science and Applications

Listen to Prof. Bengt Kasemo in this webinar on Surface Science - a field rich in science and applications.

Go there
  • QSense
QCM-D Data Analysis
Guide

QCM-D Data Analysis

We put together guidelines for you on how to evaluate which method to use, and what happens if you choose the wrong approach.

Download
  • QSense
QCM-D as a Tool to Study the Binding of Viruses
Webinar

QCM-D as a Tool to Study the Binding of Viruses

Hear researcher Gustaf Rydell, on how they used QCM-D to study interactions between virus particles and membrane associated glycolipids.

Go there
  • QSense
Key Publications on the Formation of Supported Lipid Bilayers
Overview

Key Publications on the Formation of Supported Lipid Bilayers

We gathered 8 research studies where QCM-D was used as a central analysis method.

Get it
  • QSense
Characterization of Surfaces and Surface Reactions in Energy Storage
Webinar

Characterization of Surfaces and Surface Reactions in Energy Storage

Learn how QCM-D can be used to characterize surfaces and reactions for energy storage from Dr. Archana Jaiswal, Nanoscience Instruments.

Go there
  • QSense
Development of a New Method for the Formation of SLBs on Solid Support using QSense QCM-D
Video

Development of a New Method for the Formation of SLBs on Solid Support using QSense QCM-D

Watch our interview with Prof. Nam-Joon Cho, Nanyang Technological University, about the SALB-project.

Watch
  • QSense
QCM-D Technology: From Fundamental Membrane Biophysics to Translational Applications
Webinar

QCM-D Technology: From Fundamental Membrane Biophysics to Translational Applications

If you work with fundamental or applied research in areas related to biophysics or biotechnology and are curious to learn more about how QCM-D technology can help you progress your work, then this webinar is for you!

Go there
  • QSense
QSense Etching Guide
Guide

QSense Etching Guide

Learn how to use QSense technology for assessment of detergent etching properties.

Download
  • QSense
QCM-D Characterization of Antimicrobial Lipid Interactions with Supported Lipid Bilayers: Towards Antiviral Applications in the Biomedical and Agricultural Sectors
Webinar

QCM-D Characterization of Antimicrobial Lipid Interactions with Supported Lipid Bilayers: Towards Antiviral Applications in the Biomedical and Agricultural Sectors

Listen to the talk from Joshua A. Jackman, Assistant Professor, School of Chemical Engineering, Sungkyunkwan University.

Go there
  • QSense
Monitoring of Polyelectrolyte Multilayer Build-up and Crosslinking using QCM-D
Case Study

Monitoring of Polyelectrolyte Multilayer Build-up and Crosslinking using QCM-D

In this note we show how PEM build-up and crosslinking can be characterized with QCM-D

Get it
  • QSense
Biomembrane Models and Interactions Therein
Webinar

Biomembrane Models and Interactions Therein

Watch the talk from Marité Cárdenas, Professor, Biomedical Science at Malmö University on biomembrane models.

Go there
  • QSense
Screening Nanoparticle - Protein Interactions
Case Study

Screening Nanoparticle - Protein Interactions

Nanomaterials may interact with, and have adverse effects on, e.g., biological systems. Here we show how a model system can be used as an early screening method to characterize the nanoparticle uptake and biodurability

Get it
  • QSense
The Sauerbrey Relation
Overview

The Sauerbrey Relation

Time to learn how the Sauerbrey relation is derived and what the parameters mean.

Get it
  • QSense
QSense Cleaning Profile
Guide

QSense Cleaning Profile

Explore a new way to evaluate product performance of detergents with our step-by-step guide.

Download
  • QSense
QCM-D Studies of Engineered Nanoparticles
Overview

QCM-D Studies of Engineered Nanoparticles

In this overview we explore three examples of nanoparticle analysis with QCM-D.

Get it
  • QSense
Analytical Methods to Characterize Lipid-based Systems
Overview

Analytical Methods to Characterize Lipid-based Systems

In this overview, Prof. Nam-Joon Cho, Nanyang Technological University, Singapore, has compiled a list of the analytical methods he uses in his research to characterize lipid-based systems.

Get it
  • QSense
Characterization of Biomolecular Interactions
Overview

Characterization of Biomolecular Interactions

Learn how biomolecular interactions can be analyzed using QSense® QCM-D technology and what information you can get.

Get it
  • QSense
QCM-D Analysis in Virus-related Research
Overview

QCM-D Analysis in Virus-related Research

We collected examples of scientific publications in basic and applied research for you.

Get it
  • QSense
Determining Cleansing Efficacy of Elfan AT 84 using a QCM-D Assay
Webinar

Determining Cleansing Efficacy of Elfan AT 84 using a QCM-D Assay

Hear Fredrik Andersson, Scientist at Global R&D, Nouryon, talk about how they used the QSense results to differentiate Elfan AT 84.

Go there
  • QSense
Analyze Surface-induced Complement Activation
Case Study

Analyze Surface-induced Complement Activation

In this note we show how QCM-D can be used to evaluate biomaterial immunogenicity

Get it
  • QSense
Adsorption and Aggregation of Monoclonal Antibodies at Silicone Oil-Water Interfaces
Webinar

Adsorption and Aggregation of Monoclonal Antibodies at Silicone Oil-Water Interfaces

Learn more about adsorption and aggregation of monoclonal antibodies at silicone oil-water interfaces with Ph.D. Aadithya Kannan at Genentech.

Go there
  • QSense
How do we Stop the Next Pandemic from an Unknown Virus?
Webinar

How do we Stop the Next Pandemic from an Unknown Virus?

Listen to the webinar from Prof Nam-Joon Cho on how his group work with preventing future pandemics.

Go there
  • QSense
Characterization of Polymer Layer Swelling, Crosslinking and Collapse
Case Study

Characterization of Polymer Layer Swelling, Crosslinking and Collapse

Polymer brush response to ambient changes can be characterized with QCM-D. Here we show how

Get it
  • QSense
EQCM-D Analysis in Battery Development
Webinar

EQCM-D Analysis in Battery Development

In this webinar, we take a closer look at EQCM - a highly sensitive and non-invasive analysis method that has helped answer battery-related research questions for decades.

Go there
  • QSense
Analyzing Cleaning of Hard Surfaces with QSense
Case Study

Analyzing Cleaning of Hard Surfaces with QSense

Learn how to assess cleaning efficiency using model and standardized stains.

Get it
  • QSense
QSense Analysis in CMP
Overview

QSense Analysis in CMP

In this overview, we present how QSense® QCM-D technology can be used in molecule-surface interaction analysis and optimization of CMP related processes.

Get it
  • QSense
The Dissipation Factor in QCM-D Technology
Overview

The Dissipation Factor in QCM-D Technology

In this overview, we take a closer look at the behavior of the sensor oscillation at various types of loads and investigate what the D-factor reveals.

Get it
  • QSense
Temperature Stability in QCM Measurements
Overview

Temperature Stability in QCM Measurements

Achieve reliable and reproducible QCM measurements by controlling the temperature.

Get it
  • QSense
What is Dissipation?
Overview

What is Dissipation?

This is your chance to find out what it is, why it is important, and how it can be measured.

Get it
  • QSense
What is a Viscoelastic material?
Overview

What is a Viscoelastic material?

Ice, wood and a disks in the human spine are all viscoelastic materials. What does it really mean?

Get it
  • QSense
How to Generate Quality QCM-D Data
Guide

How to Generate Quality QCM-D Data

Follow our checklist for high-quality data and reproducible measurements.

Download
  • QSense
QCM-D vs other QCMs
White Paper

QCM-D vs other QCMs

We sort out the the differences between QCM methods to answer the question - does it matter which one I use?

Download
  • QSense
Assessing the inflammatory responses induced by biomaterials in contact with human blood using in vitro assays including QCM-D
Webinar

Assessing the inflammatory responses induced by biomaterials in contact with human blood using in vitro assays including QCM-D

If you work with fundamental or applied research related to biomaterials, biotechnology or biophysics, and are curious to learn more about how QCM-D technology can help you progress your work, then this webinar is for you.

Go there
  • QSense
Implementing quartz crystal microbalance with dissipation monitoring for the development of novel biosensing assays
Webinar

Implementing quartz crystal microbalance with dissipation monitoring for the development of novel biosensing assays

Exosomes have shown great importance in intercellular communication and disease transmission. As result, there has been a significant increase in trying novel biosensing platforms that can detect exosomal content such as proteins and nucleic acid with a view toward application in diagnostic assays. This webinar by Prof. Guldinwill present recent efforts on implementing quartz crystal microbalance with dissipation monitoring (QCM-D) for reliable biosensing. The presenter has recently developed an approach, based on QCM-D, for the stepwise functionalization of surface immobilization and subsequent uptake and release of binding partners.

Go there
  • QSense
QCM-D Publications in Battery Research
List

QCM-D Publications in Battery Research

Explore our list of 33 recent publications that exemplify the usage of QCM-D technology in various aspects of battery research.

Get it
  • QSense
How to read a QCM Specification
Guide

How to read a QCM Specification

There are key parameters to keep an eye on when investing in a new QCM instrument. Learn what they mean, and why they are important.

Download
  • QSense
Dfind Basic Training Course
Webinar

Dfind Basic Training Course

Learn the basics of Dfind, get a walk-through of the software and watch two live demo examples.

Go there
  • QSense
Information Obtained with QSense QCM-D
Overview

Information Obtained with QSense QCM-D

We have summarized the parameters and processes that can be studied with QCM-D for you.

Get it
  • QSense
How to Characterize Lipid-Based Systems with QCM-D
Overview

How to Characterize Lipid-Based Systems with QCM-D

You get a brief overview of how to analyze lipid layer formation dynamics, structure and layer quality.

Get it
  • QSense
QCM-D in Research
List

QCM-D in Research

Explore the work of Prof. Nam-Joon Cho and his research group through their publications.

Get it
  • QSense
Biomaterials – Man-made Materials for Regenerative Medicine
Webinar

Biomaterials – Man-made Materials for Regenerative Medicine

Learn from Prof. Bengt Kasemo in this webinar on Biomaterials – man-made materials for regenerative medicine.

Go there