You want to maximize the available experimental contextThe possibility to combine QCM-D with other techniques invites you to expand the understanding of your surface processes
You want to study under a wide range of conditions
Depending on your specific research needs you can create a QSense Explorer configuration compatible with temperatures up to 150° C and variable gas phase pressures. You can also build your instrument with the ability to withstand harsh solvents
Most suitable when
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3 reasons to invest
Superior data quality and versatility
Combine with other techniques
Run experiments under special conditions
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Measurement range and capacity
|Working temperature||15 to 65 °C, 4 to 150 °C using accessory chamber (QSense High Temperature chamber)|
|Sensors (frequency range)||5 MHz (1-72)|
|Number of measured
|7, allows for full viscoelastic modeling|
Sample and fluidics
|Minimum sample volume, stagnant mode||~ 40 μl
~ 10 μl using add-on module (QSense Open module)
|Minimum sample volume, flow mode||~ 200 μl|
|Flow rates||25-150 μl/min applicable for QSense setup (Peristaltic pump settable to 0-1 ml/min)|
|Maximum time resolution||300 datapoints per second (each datapoint represents an f and D value)|
|LOD (3 x noise)||1.56 ng/cm2|
|Sensitivity/limit of detection and noise||See the graph below|
Frequency: 0.03 Hz
Mass: 0.5 ng/cm2
|Long-term stability*||Frequency: < 1 Hz/h
Dissipation: < 0.15∙10-6
Temperature: < 0.02˚C/h
* The temperature stability depends on variations in how the ambient affects the warming or cooling of the chamber. The specified temperature stability may not be reached if the room temperature changes more than ± 1° C, if there is a draft or a heat source nearby. All specifications are subject to change without notice.
Optimal real-life performance
Applying a higher sample rate inevitably leads to higher noise and thus a compromised limit of detection (LOD). What aspect to prioritize depends on the studied surface interaction process. High time resolution may not be critical if very slow changes are studied, and a high measurement sensitivity may not be important if large changes are to be measured. With the 5 Speed-to-Noise modes you can select the right setting to maximize real-life performance for your measurement.
The below figure and table describe the real-measurement performance of QSense Explorer for each acquisition mode. This is much more interesting than maximum values in a specification to understand what to expect from your instrument in a real measurement situation.
Speed and limit of detection (LOD) per acquisition mode. Limit of detection is set to 1 S.D. of the baseline noise.
Performance characteristics. Measurements were performed with QSX 303 SiO2 sensors at 20°C temperature, and in deionized water at a flow of 15µL/min. Each measurement mode was measured for approximately 5 minutes.
QSoft and Dfind software
QSense softwares are designed for you to make the most out of your QCM-D measurements. QSoft is collecting your data whereas Dfind makes your analysis easier.
- A complete analysis toolbox
One software for all your needs
- Intuitive interface
Dfind supports you all the way through your analysis process - from data preparation to final reporting
- Guided modelling
To take you through your analysis step by step
- Material library
Configuring your modelling setup is easy, just select your sample material from the list
Visualizes your results throughout the whole analysis
- Smart tools
Dfind offers several analysis methods including shifts, rates and slopes to help you extract the information you need
- Analyze all data in one go
To save your time, Dfind allows you to review, model and analyze multiple data sets in one go
- PC with 64-bit Windows 7 SP1, 8, 8.1 or 10
- At least 1366×768 px screen resolution
- At least 4 GB RAM
- 1920×1080 Full HD screen resolution.
- At least 8 GB RAM
- At least 50 GB HD space
- Core i5 5th generation Intel (or comparable) processor or better
For simultaneous QCM-D and electrochemistry measurements on the same surface. Enables cyclic voltammetry and electrochemical impedance measurements to explore polymer behavior, electrostatic interactions, corrosion, etc.
Enables simultaneous QCM-D and ellipsometry measurements on the same surface, which allows for quantification of solvent content in the film. It also gives a refined analysis of the morphological changes of the adsorbed film.
The Window Module allows optical access to the sensor surface through a sapphire window. It enables experiments with UV-induced reactions and when used in the QSense Explorer chamber, the compact design also enables microscopy studies of reactions on the sensor.
High Temperature Chamber
With the High Temperature Chamber you can perform measurements in an extended temperature range of 4-150°C.
What others say
Our instruments are present at many prestigious universities and research facilities worldwide. Take a minute to find out what others say about QSense.
Sivashankar Krishnamoorthy on QSense
"We use the QSense Explorer and Analyzer systems. We could get started rather quickly, thanks to the ease of using the systems."
Dr Sivashankar Krishnamoorthy, Luxembourg Institute of Science and Technology
"We spent time to understand different ways to customize the sensor chips, assay configuration, and flow routines to rational design of nanoplasmonic and nanopatterned sensors. Have had a great experience so far."
Marité Cárdenas on QSense
"QSense instruments are a great tool for our biophysical research. They enable rapid screening for biomolecular interaction at lipid bilayers and also allow optimizing the parameters for deposition of thin films."
Professor Dr. Marité Cárdenas, Health and Society, Malmö University
"The instrument is easy to use, and has a long working life as long as you follow the maintenance instructions! The technical staff at Biolin Scientific are a pleasure to work with: They are nice and always give quick feedback and support."
Kenichi Sakai on QSense
"We regard QCM-D as a valuable measuring tool due to its high sensitivity and stability and find it applicable for versatile studies because of its availabilities of sensors with different types of surfaces. In this context I would say QCM-D is the best suitable solution for simulating a variety of nanoscale interaction behaviors both real-time & in-situ."
Kenichi Sakai, Associate Professor, Tokyo University of Science
"We are working on academic research in the field of colloid and interface chemistry and our main work is synthesis of novel surfactants and characterization of their properties. We use QCM-D as a must-tool to comprehend molecular adsorption/desorption behaviors specifically observed at a solid-liquid interface."
Jodie Lutkenhaus on QSense
"We can monitor the mass change of our system in real-time. I can tell you that for every electron moved, this amount of mass changed. That’s powerful. You can’t really get that with any other system."
Jodie Lutkenhaus, Associate Professor, Texas A&M University
"We use the QSense high temperature model that allows us to investigate polyelectrolyte complexes and their response to temperature. We’re also using the electrochemistry module so we can run our standard electrochemical measurements at the same time as we run the QCM-D."
Malkiat Johal on QSense
"I have found QSense to be one of the best techniques for an undergraduate lab because it’s turnkey and it requires very little maintenance."
Malkiat Johal, Professor of Chemistry, Pomona College
"The operating principles are straightforward and the students can focus on the science. And so, that’s something that we have been really happy with, it really works in this kind of setting. It’s an ideal method for an undergraduate surface science lab."
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