In a hurry?

Discover QSense High  Pressure and all of its advantages in this 3 minutes long video.

phenomena

  • Adsorption
  • Desorption
  • Binding and interactions
  • Swelling
  • Collapse
  • Degradation, corrosion and etching

Measure in High Pressure & Temperature

Explorer High-Pressure environments
Study in High temperatures

Key features

  • Measure mass, thickness, and viscoelastic properties of rigid and soft films

    7-harmonic QCM-D with QSense Decay technology enables qualitative and quantitative analysis
  • High temperature chamber

    Measure up to 150°C
  • Maintain liquid phase

    Use pressure to maintain liquid state in higher temperatures
  • High pressure module

    Measure between 90-200 bar to explore real-life pressure conditions
  • Full high pressure set up

    All you need to be able to work with liquid flow at high pressures
  • Broadest offer of sensor surfaces and coatings

    Set up model systems that are as close as possible to real-world conditions
Complete analysis set-up

QSOFT AND DFIND SOFTWARE

HP gif

QSense software is tailored to help you maximize the potential of your QCM-D measurements. With QSoft capturing your data and Dfind simplifying your analysis, you can streamline your research process effortlessly.

measurement conditions

  • Flow mode
  • Stagnant mode
  • Liquid phase
  • Harsh chemicals
  • Low temperature
  • High temperature
  • Variable pressure
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A closer look

Let's dive into the specifications for QSense High Pressure. 

Compare QSense range

Measurement range and capacity

Measurement channels
Working temperature* 4 to 150 °C, controlled via the software, stability ± 0.02 °C
Working pressure 90 to 200 bar (with the alternative peristaltic pump measurements can also be performed at ambient pressure)
Sensors (frequency range) 5 MHz (1-72)
Number of measured
harmonics
7, allows for full viscoelastic modeling

Sample and fluidics 

Minimum sample volume, stagnant mode ~ 40 μl
Minimum sample volume, flow mode ~ 200 μl
Flow rates 25-150 μl/min applicable for QSense setup (Peristaltic pump settable to 0-1 ml/min)
Additional info Note that the system liquid to be used in the QSense High Pressure System may require a fume hood or point exhaustion

Performance characteristics 

Maximum time resolution 300 datapoints per second (each datapoint represents an f and D value)
Sensitivity/limit of detection and noise Refer to performance in different modes, for more info visit QSense Explorer product page
Long-term stability* Frequency: < 1 Hz/h
Dissipation: < 0.15∙10-6
Temperature: < 0.02˚C/h

*The temperature stability depends on variations in how the ambient affects the warming or cooling of the chamber. The specified temperature stability may not be reached if the room temperature changes more than ± 1° C, if there is a draft or a heat source nearby. The specifications above are valid for this configuration. All specifications are subject to change without notice.

Standard sensors
The sensor is at the heart of the QCM-D experiment. Browse the widest range of sensors on the market to find out which sensor material and coating is best suited for your research.
We offer over 50 standard sensors - from various metals, oxides and carbides to polymers, functionalized coatings and and standardized soils. Our sensors are developed and produced to provide you with stable, reliable and reproducible data. Full performance is ensured through extensive quality controls and guaranteed for one-time use according to the recommendations.
Customized sensors
Sensor materials and coatings based on your specific needs
Read more

Want the see more?

Explore our sensors

QSoft and Dfind software

QSense softwares are designed for you to make the most out of your QCM-D measurements. QSoft is collecting your data whereas Dfind makes your analysis easier. 

Dfind features

  • A complete analysis toolbox 
    One software for all your needs 
  • Intuitive interface 
    Dfind supports you all the way through your analysis process - from data preparation to final reporting
  • Guided modelling
    To take you through your analysis step by step 
  • Material library
    Configuring your modelling setup is easy, just select your sample material from the list
  • Autoplotting
    Visualizes your results throughout the whole analysis
  • Smart tools
    Dfind offers several analysis methods including shifts, rates and slopes to help you extract the information you need
  • Analyze all data in one go
    To save your time, Dfind allows you to review, model and analyze multiple data sets in one go
Would you like to know more about the details of Dfind and learn how the subscription works?

Learn more about Dfind!

Computer requirements

Required
  • PC with 64-bit Windows 7 SP1, 8, 8.1 or 10
  • At least 1366×768 px screen resolution
  • At least 4 GB RAM


Recommended
  • 1920×1080 Full HD screen resolution.
  • At least 8 GB RAM
  • At least 50 GB HD space
  • Core i5 5th generation Intel (or comparable) processor or better

Add more possibilities

QSense High Pressure is based on our most versatile QCM-D instrument QSense Explorer. If you want to perform measurements in ambient pressure, you can always expand your possibilities with our Explorer chamber. We have selected a few add-ons you might be interested in.  

What our customers say

Our instruments are present at many prestigious universities and research facilities worldwide. Take a minute to find out what others say about QSense High Pressure. 

Prof. Dennis R. Heldman, The Ohio State University

"Our laboratory uses the QSense High Pressure QCM-D system for the study of the reactions occurring at the interface between a surface and a high-protein liquid food. Information about the rate of fouling on the surface and the composition of the foulant has provided new and important insights before scale-up to pilot and commercial-scale experiments with a focus on the contributions of flow characteristics over the surface. These new and different insights provide our laboratory and others with a completely new and different dimension to our research.”

ohio-state-university-logo

The Ohio State University

Ohio State University, OSU, is the highest-ranked public university in Ohio and home to the Department of Food Science and Technology. The work of Prof. Dennis R. Heldman centers around food engineering, with emphasis on process design to achieve maximum efficiency and optimum food product quality.

Learn more

We have gathered all our in-depth knowledge associated with QSense High Pressure. Browse around amongst guides, overviews and white papers to find a topic of interest. 

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How Excipients, Surfaces and Formulation Conditions Affect Therapeutic Proteins
Webinar

How Excipients, Surfaces and Formulation Conditions Affect Therapeutic Proteins

Can QCM-D quantify how surfactants affect protein-surface interaction? Watch this webinar with Dr. Archana Jaiswal to find out more.

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Basics of QCM-D
Webinar

Basics of QCM-D

Learn the fundamentals of the technology, its possibilities and limitations and get a deeper understanding of nanometer layers.

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How to Optimize the QCM-D Baseline Stability
Guide

How to Optimize the QCM-D Baseline Stability

9 steps to eliminate error sources and optimize reproducibility

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The Working Principles of QCM and QCM-D
Overview

The Working Principles of QCM and QCM-D

Learn the fundamentals of how the technologies work, and what is the difference between them.

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QCM-D vs other QCMs
Overview

QCM-D vs other QCMs

Let this brief overview guide you to your most suitable choice of QCM.

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What is Piezoelectricity?
Overview

What is Piezoelectricity?

Bone, wood and quartz are all piezoelectric materials. Learn about piezoelectricity and how it works

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How QCM Results are Influenced by Layer Distribution
Overview

How QCM Results are Influenced by Layer Distribution

The distribution of the measured layer is key to your results. Discover why and how to handle it.

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Why the Resonance Frequency of a QCM Sensor is 5MHz
Overview

Why the Resonance Frequency of a QCM Sensor is 5MHz

What determines the value of the fundamental resonance frequency? In this overview, we explain the theory behind the number.

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  • QSense
Characterization of Polymer-based Systems
Overview

Characterization of Polymer-based Systems

Analyze layer build-up, conformation and molecular interaction with QSense QCM-D

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Using QCM-D in the Food Industry
Webinar

Using QCM-D in the Food Industry

Learn more about QCM-D in food industry with studies of shelf life from Cornell University.

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What is Biocompatibility?
Overview

What is Biocompatibility?

In this overview we explain how biocompatibility is defined and give examples of what the property entails.

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Why it is Useful to use Multiple Overtones in QCM Measurements?
Overview

Why it is Useful to use Multiple Overtones in QCM Measurements?

Learn what information the overtones offer in this overview.

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Nanocellulose Research with QCM-D
Webinar

Nanocellulose Research with QCM-D

Watch our webinar on Nanocellulose Research with QCM-D where we will discuss thin films of cellulose nanofibrils development, and their characterization. 

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  • QSense
Analysis of Surfactant-Surface Interactions with QSense
Case Study

Analysis of Surfactant-Surface Interactions with QSense

Find out how to analyze surfactant interaction with surfaces at the nanoscale.

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Getting Started with QSense Dfind
Webinar

Getting Started with QSense Dfind

QSense Dfind assists you with raw data review, modeling, information extraction and generating reports. Get started with the webinar by Patricia Passanesi, Application Scientist at Biolin Scientific

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  • QSense
QCM-D Data Analysis
Guide

QCM-D Data Analysis

We put together guidelines for you on how to evaluate which method to use, and what happens if you choose the wrong approach.

Download
  • QSense
 QCM-D as a Tool to Study the Binding of Viruses
Webinar

QCM-D as a Tool to Study the Binding of Viruses

Hear researcher Gustaf Rydell, on how they used QCM-D to study interactions between virus particles and membrane associated glycolipids.

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  • QSense
Characterization of Surfaces and Surface Reactions in Energy Storage
Webinar

Characterization of Surfaces and Surface Reactions in Energy Storage

Learn how QCM-D can be used to characterize surfaces and reactions for energy storage from Dr. Archana Jaiswal, Nanoscience Instruments.

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QSense Etching Guide
Guide

QSense Etching Guide

Learn how to use QSense technology for assessment of detergent etching properties.

Download
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QCM-D Characterization of Antimicrobial Lipid Interactions with Supported Lipid Bilayers: Towards Antiviral Applications in the Biomedical and Agricultural Sectors
Webinar

QCM-D Characterization of Antimicrobial Lipid Interactions with Supported Lipid Bilayers: Towards Antiviral Applications in the Biomedical and Agricultural Sectors

Listen to the talk from Joshua A. Jackman, Assistant Professor, School of Chemical Engineering, Sungkyunkwan University.

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The Sauerbrey Relation
Overview

The Sauerbrey Relation

Time to learn how the Sauerbrey relation is derived and what the parameters mean.

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  • QSense
QCM-D Studies of Engineered Nanoparticles
Overview

QCM-D Studies of Engineered Nanoparticles

In this overview we explore three examples of nanoparticle analysis with QCM-D.

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  • QSense
Characterization of Biomolecular Interactions
Overview

Characterization of Biomolecular Interactions

Learn how biomolecular interactions can be analyzed using QSense® QCM-D technology and what information you can get.

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  • Attension
Working with QCM-D and Contact Angle Measurements under High Pressure - Oil and Gas Applications
Webinar

Working with QCM-D and Contact Angle Measurements under High Pressure - Oil and Gas Applications

Explore the possibilities of performing measurements in high pressure, techniques especially suitable for oil and gas applications.

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  • QSense
Adsorption and Aggregation of Monoclonal Antibodies at Silicone Oil-Water Interfaces
Webinar

Adsorption and Aggregation of Monoclonal Antibodies at Silicone Oil-Water Interfaces

Learn more about adsorption and aggregation of monoclonal antibodies at silicone oil-water interfaces with Ph.D. Aadithya Kannan at Genentech.

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  • QSense
QSense Analysis in CMP
Overview

QSense Analysis in CMP

In this overview, we present how QSense® QCM-D technology can be used in molecule-surface interaction analysis and optimization of CMP related processes.

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The Dissipation Factor in QCM-D Technology
Overview

The Dissipation Factor in QCM-D Technology

In this overview, we take a closer look at the behavior of the sensor oscillation at various types of loads and investigate what the D-factor reveals.

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  • QSense
Temperature Stability in QCM Measurements
Overview

Temperature Stability in QCM Measurements

Achieve reliable and reproducible QCM measurements by controlling the temperature.

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  • QSense
What is Dissipation?
Overview

What is Dissipation?

This is your chance to find out what it is, why it is important, and how it can be measured.

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  • QSense
What is a Viscoelastic material?
Overview

What is a Viscoelastic material?

Ice, wood and a disks in the human spine are all viscoelastic materials. What does it really mean?

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  • QSense
How to Generate Quality QCM-D Data
Guide

How to Generate Quality QCM-D Data

Follow our checklist for high-quality data and reproducible measurements.

Download
  • QSense
QCM-D vs other QCMs
White Paper

QCM-D vs other QCMs

We sort out the the differences between QCM methods to answer the question - does it matter which one I use?

Download
  • QSense
QCM-D Publications in Battery Research
List

QCM-D Publications in Battery Research

Explore our list of 33 recent publications that exemplify the usage of QCM-D technology in various aspects of battery research.

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How to read a QCM Specification
Guide

How to read a QCM Specification

There are key parameters to keep an eye on when investing in a new QCM instrument. Learn what they mean, and why they are important.

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Dfind Basic Training Course
Webinar

Dfind Basic Training Course

Learn the basics of Dfind, get a walk-through of the software and watch two live demo examples.

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Information Obtained with QSense QCM-D
Overview

Information Obtained with QSense QCM-D

We have summarized the parameters and processes that can be studied with QCM-D for you.

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  • QSense
Biomaterials – Man-made Materials for Regenerative Medicine
Webinar

Biomaterials – Man-made Materials for Regenerative Medicine

Learn from Prof. Bengt Kasemo in this webinar on Biomaterials – man-made materials for regenerative medicine.

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