Most suitable when

  • You are striving to explore real-life high pressure and high temperature conditions
    For the standard configuration the pressure and temperature can be set to a maximum of 200 Bar and 150 °C respectively, but the instrument can also be configured after your specific needs
  • You want to expand your possibilities
    The system is built upon the versatile and modular QSense Explorer providing plenty of add-ons if you want to widen your view 

A quick view

Get an overview of the QSense High Pressure system with this 2-minute video. Watch it in fullscreen for the best experience! 

3 reasons to invest

Make smarter decisions

Whether you are struggling to increase oil yield, to prevent fouling of pipes or to find an optimal lubricant for engines, it is valuable to understand your processes better. With QSense High Pressure you can make smarter decisions based on information about the surface interaction processes that are key to your outcome.
 

Explore real-life conditions

We are providing standard and custom made sensors to fit your needs. Study what happens in real-time to draw conclusions and optimize your process based on QCM-D results. Analyzing under relevant conditions can make the whole difference. That is why we created the QSense High Pressure. 
 

Add a highly sensitive tool 

Recording the changes of frequency and dissipation of a quartz crystal sensor, the technology offers you a new set of eyes in the studies of surface events such as adsorption and desorption at the nanoscale. 
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A closer look

Let's dive into the specifications for QSense High Pressure. 

Compare QSense range

Measurement range and capacity

Measurement channels
Working temperature* 4 to 150 °C, controlled via the software, stability ± 0.02 °C
Working pressure 90 to 200 bar (with the alternative peristaltic pump measurements can also be performed at ambient pressure)
Sensors (frequency range) 5 MHz (1-72)
Number of measured
harmonics
7, allows for full viscoelastic modeling

Sample and fluidics 

Minimum sample volume, stagnant mode ~ 40 μl
Minimum sample volume, flow mode ~ 200 μl
Flow rates 25-150 μl/min applicable for QSense setup (Peristaltic pump settable to 0-1 ml/min)
Additional info Note that the system liquid to be used in the QSense High Pressure System may require a fume hood or point exhaustion

Performance characteristics 

Maximum time resolution 300 datapoints per second (each datapoint represents an f and D value)
Sensitivity/limit of detection and noise Refer to performance in different modes, for more info visit QSense Explorer product page
Long-term stability* Frequency: < 1 Hz/h
Dissipation: < 0.15∙10-6
Temperature: < 0.02˚C/h

*The temperature stability depends on variations in how the ambient affects the warming or cooling of the chamber. The specified temperature stability may not be reached if the room temperature changes more than ± 1° C, if there is a draft or a heat source nearby. The specifications above are valid for this configuration. All specifications are subject to change without notice.

Standard sensors
The sensor is at the heart of the QCM-D experiment. Browse the widest range of sensors on the market to find out which sensor material and coating is best suited for your research.
We offer over 50 standard sensors - from various metals, oxides and carbides to polymers, functionalized coatings and and standardized soils. Our sensors are developed and produced to provide you with stable, reliable and reproducible data. Full performance is ensured through extensive quality controls and guaranteed for one-time use according to the recommendations.
Customized sensors
Sensor materials and coatings based on your specific needs
Read more

Want the see more?

Explore our sensors

QSoft and Dfind software

QSense softwares are designed for you to make the most out of your QCM-D measurements. QSoft is collecting your data whereas Dfind makes your analysis easier. 

Dfind features

  • A complete analysis toolbox 
    One software for all your needs 
  • Intuitive interface 
    Dfind supports you all the way through your analysis process - from data preparation to final reporting
  • Guided modelling
    To take you through your analysis step by step 
  • Material library
    Configuring your modelling setup is easy, just select your sample material from the list
  • Autoplotting
    Visualizes your results throughout the whole analysis
  • Smart tools
    Dfind offers several analysis methods including shifts, rates and slopes to help you extract the information you need
  • Analyze all data in one go
    To save your time, Dfind allows you to review, model and analyze multiple data sets in one go
Would you like to know more about the details of Dfind and learn how the subscription works?

Learn more about Dfind!

Computer requirements

Required
  • PC with 64-bit Windows 7 SP1, 8, 8.1 or 10
  • At least 1366×768 px screen resolution
  • At least 4 GB RAM


Recommended
  • 1920×1080 Full HD screen resolution.
  • At least 8 GB RAM
  • At least 50 GB HD space
  • Core i5 5th generation Intel (or comparable) processor or better

Add more possibilities

QSense High Pressure is based on our most versatile QCM-D instrument QSense Explorer. If you want to perform measurements in ambient pressure, you can always expand your possibilities with our Explorer chamber. We have selected a few add-ons you might be interested in.  

What our customers say

Our instruments are present at many prestigious universities and research facilities worldwide. Take a minute to find out what others say about QSense High Pressure. 

Prof. Dennis R. Heldman, The Ohio State University

"Our laboratory uses the QSense High Pressure QCM-D system for the study of the reactions occurring at the interface between a surface and a high-protein liquid food. Information about the rate of fouling on the surface and the composition of the foulant has provided new and important insights before scale-up to pilot and commercial-scale experiments with a focus on the contributions of flow characteristics over the surface. These new and different insights provide our laboratory and others with a completely new and different dimension to our research.”

ohio-state-university-logo

The Ohio State University

Ohio State University, OSU, is the highest-ranked public university in Ohio and home to the Department of Food Science and Technology. The work of Prof. Dennis R. Heldman centers around food engineering, with emphasis on process design to achieve maximum efficiency and optimum food product quality.

Learn more

We have gathered all our in-depth knowledge associated with QSense High Pressure. Browse around amongst guides, overviews and white papers to find a topic of interest. 

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How to read a QCM Specification
Guide

How to read a QCM Specification

There are key parameters to keep an eye on when investing in a new QCM instrument. Learn what they mean, and why they are important.

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Information Obtained with QSense QCM-D
Overview

Information Obtained with QSense QCM-D

We have summarized the parameters and processes that can be studied with QCM-D for you.

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  • QSense
QCM-D vs other QCMs
White Paper

QCM-D vs other QCMs

We sort out the the differences between QCM methods to answer the question - does it matter which one I use?

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The Sauerbrey Relation
Overview

The Sauerbrey Relation

Time to learn how the Sauerbrey relation is derived and what the parameters mean.

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QCM-D Data Analysis
Guide

QCM-D Data Analysis

We put together guidelines for you on how to evaluate which method to use, and what happens if you choose the wrong approach.

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QCM-D Studies of Engineered Nanoparticles
Overview

QCM-D Studies of Engineered Nanoparticles

In this overview we explore three examples of nanoparticle analysis with QCM-D.

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QSense Etching Guide
Guide

QSense Etching Guide

Learn how to use QSense technology for assessment of detergent etching properties.

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The Working Principles of QCM and QCM-D
Overview

The Working Principles of QCM and QCM-D

Learn the fundamentals of how the technologies work, and what is the difference between them.

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  • QSense
What is Dissipation?
Overview

What is Dissipation?

This is your chance to find out what it is, why it is important, and how it can be measured.

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  • QSense
Temperature Stability in QCM Measurements
Overview

Temperature Stability in QCM Measurements

Achieve reliable and reproducible QCM measurements by controlling the temperature.

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  • QSense
How to Generate Quality QCM-D Data
Guide

How to Generate Quality QCM-D Data

Follow our checklist for high-quality data and reproducible measurements.

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How QCM Results are Influenced by Layer Distribution
Overview

How QCM Results are Influenced by Layer Distribution

The distribution of the measured layer is key to your results. Discover why and how to handle it.

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What is Piezoelectricity?
Overview

What is Piezoelectricity?

Bone, wood and quartz are all piezoelectric materials. Learn about piezoelectricity and how it works

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QCM-D vs other QCMs
Overview

QCM-D vs other QCMs

Let this brief overview guide you to your most suitable choice of QCM.

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  • QSense
How to Optimize the QCM-D Baseline Stability
Guide

How to Optimize the QCM-D Baseline Stability

9 steps to eliminate error sources and optimize reproducibility

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Characterization of Polymer-based Systems
Overview

Characterization of Polymer-based Systems

Analyze layer build-up, conformation and molecular interaction with QSense QCM-D

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  • QSense
Analysis of Surfactant-Surface Interactions with QSense
Case Study

Analysis of Surfactant-Surface Interactions with QSense

Find out how to analyze surfactant interaction with surfaces at the nanoscale.

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What is a Viscoelastic material?
Overview

What is a Viscoelastic material?

Ice, wood and a disks in the human spine are all viscoelastic materials. What does it really mean?

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  • QSense
Characterization of Biomolecular Interactions
Overview

Characterization of Biomolecular Interactions

Learn how biomolecular interactions can be analyzed using QSense® QCM-D technology and what information you can get.

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Dfind Basic Training Course
Webinar

Dfind Basic Training Course

Learn the basics of Dfind, get a walk-through of the software and watch two live demo examples.

Go there
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Basics of QCM-D
Webinar

Basics of QCM-D

Learn the fundamentals of the technology, its possibilities and limitations and get a deeper understanding of nanometer layers.

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  • QSense
Biomaterials – Man-made Materials for Regenerative Medicine
Webinar

Biomaterials – Man-made Materials for Regenerative Medicine

Learn from Prof. Bengt Kasemo in this webinar on Biomaterials – man-made materials for regenerative medicine.

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 QCM-D as a Tool to Study the Binding of Viruses
Webinar

QCM-D as a Tool to Study the Binding of Viruses

Hear researcher Gustaf Rydell, on how they used QCM-D to study interactions between virus particles and membrane associated glycolipids.

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Nanocellulose Research with QCM-D
Webinar

Nanocellulose Research with QCM-D

Watch our webinar on Nanocellulose Research with QCM-D where we will discuss thin films of cellulose nanofibrils development, and their characterization. 

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  • QSense
Using QCM-D in the Food Industry
Webinar

Using QCM-D in the Food Industry

Learn more about QCM-D in food industry with studies of shelf life from Cornell University.

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Characterization of Surfaces and Surface Reactions in Energy Storage
Webinar

Characterization of Surfaces and Surface Reactions in Energy Storage

Learn how QCM-D can be used to characterize surfaces and reactions for energy storage from Dr. Archana Jaiswal, Nanoscience Instruments.

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How Excipients, Surfaces and Formulation Conditions Affect Therapeutic Proteins
Webinar

How Excipients, Surfaces and Formulation Conditions Affect Therapeutic Proteins

Can QCM-D quantify how surfactants affect protein-surface interaction? Watch this webinar with Dr. Archana Jaiswal to find out more.

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  • QSense
What is Biocompatibility?
Overview

What is Biocompatibility?

In this overview we explain how biocompatibility is defined and give examples of what the property entails.

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  • QSense
The Dissipation Factor in QCM-D Technology
Overview

The Dissipation Factor in QCM-D Technology

In this overview, we take a closer look at the behavior of the sensor oscillation at various types of loads and investigate what the D-factor reveals.

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  • QSense
Why it is Useful to use Multiple Overtones in QCM Measurements?
Overview

Why it is Useful to use Multiple Overtones in QCM Measurements?

Learn what information the overtones offer in this overview.

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  • QSense
QSense Analysis in CMP
Overview

QSense Analysis in CMP

In this overview, we present how QSense® QCM-D technology can be used in molecule-surface interaction analysis and optimization of CMP related processes.

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  • QSense
Why the Resonance Frequency of a QCM Sensor is 5MHz
Overview

Why the Resonance Frequency of a QCM Sensor is 5MHz

What determines the value of the fundamental resonance frequency? In this overview, we explain the theory behind the number.

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  • Attension
Working with QCM-D and Contact Angle Measurements under High Pressure - Oil and Gas Applications
Webinar

Working with QCM-D and Contact Angle Measurements under High Pressure - Oil and Gas Applications

Explore the possibilities of performing measurements in high pressure, techniques especially suitable for oil and gas applications.

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  • QSense
Adsorption and Aggregation of Monoclonal Antibodies at Silicone Oil-Water Interfaces
Webinar

Adsorption and Aggregation of Monoclonal Antibodies at Silicone Oil-Water Interfaces

Learn more about adsorption and aggregation of monoclonal antibodies at silicone oil-water interfaces with Ph.D. Aadithya Kannan at Genentech.

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  • QSense
QCM-D Publications in Battery Research
List

QCM-D Publications in Battery Research

Explore our list of 33 recent publications that exemplify the usage of QCM-D technology in various aspects of battery research.

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Getting Started with QSense Dfind
Webinar

Getting Started with QSense Dfind

QSense Dfind assists you with raw data review, modeling, information extraction and generating reports. Get started with the webinar by Patricia Passanesi, Application Scientist at Biolin Scientific

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QCM-D Characterization of Antimicrobial Lipid Interactions with Supported Lipid Bilayers: Towards Antiviral Applications in the Biomedical and Agricultural Sectors
Webinar

QCM-D Characterization of Antimicrobial Lipid Interactions with Supported Lipid Bilayers: Towards Antiviral Applications in the Biomedical and Agricultural Sectors

Listen to the talk from Joshua A. Jackman, Assistant Professor, School of Chemical Engineering, Sungkyunkwan University.

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