Overview

Most suitable when

  • You are striving to explore real-life high pressure and high temperature conditions
    For the standard configuration the pressure and temperature can be set to a maximum of 200 Bar and 150 °C respectively, but the instrument can also be configured after your specific needs
  • You want to expand your possibilities
    The system is built upon the versatile and modular QSense Explorer providing plenty of add-ons if you want to widen your view 

A quick view

Get an overview of the QSense High Pressure system with this 2-minute video. Watch it in fullscreen for the best experience! 

3 reasons to invest

Make smarter decisions

Whether you are struggling to increase oil yield, to prevent fouling of pipes or to find an optimal lubricant for engines, it is valuable to understand your processes better. With QSense High Pressure you can make smarter decisions based on information about the surface interaction processes that are key to your outcome.
 

Explore real-life conditions

We are providing standard and custom made sensors to fit your needs. Study what happens in real-time to draw conclusions and optimize your process based on QCM-D results. Analyzing under relevant conditions can make the whole difference. That is why we created the QSense High Pressure. 
 

Add a highly sensitive tool 

Recording the changes of frequency and dissipation of a quartz crystal sensor, the technology offers you a new set of eyes in the studies of surface events such as adsorption and desorption at the nanoscale. 

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Specifications

A closer look

Let's dive into the specifications for QSense High Pressure. 

Measurement range and capacity

Measurement channels
Working temperature* 4 to 150 °C, controlled via the software, stability ± 0.02 °C
Working pressure 90 to 200 bar (with the alternative peristaltic pump measurements can also be performed at ambient pressure)
Sensors (frequency range) 5 MHz (1-72)
Number of measured
harmonics
7, allows for full viscoelastic modeling

Sample and fluidics 

Minimum sample volume, stagnant mode ~ 40 μl
Minimum sample volume, flow mode ~ 200 μl
Flow rates 25-150 μl/min applicable for QSense setup (Peristaltic pump settable to 0-1 ml/min)

Performance characteristics 

Maximum time resolution 300 datapoints per second (each datapoint represents an f and D value)
Sensitivity/limit of detection and noise Refer to performance in different modes, for more info visit QSense Explorer product page
Long-term stability* Frequency: < 1 Hz/h
Dissipation: < 0.15∙10-6
Temperature: < 0.02˚C/h

Software

  QSoft Acquisition software Dfind Analysis software
Measurement channels Time-resolved Frequency and Dissipation for 7 harmonics Thickness (or mass), viscosity, shear modulus and the frequency dependence of the viscosity and shear modulus. Kinetics, slope, rise time and more
Computer requirements USB 2.0 PC with 64-bit
> 1366×768 px screen resolution, > 4 GB RAM
Operating system Windows 10 or later (earlier Windows versions may not fully work and support cannot be guaranteed)
Import/export Excel, BMP, JPG, WMF, GIF, PCX, PNG, TXT CSV files. Decimal separator, full stop or comma

Electrical data QSense Electronics unit

Power supply and frequency 115-120 / 220 / 230-240 V AC, 50-60 Hz
The power supply should be properly grounded

Dimensions and weight

  Height (cm) Width (cm) Depth (cm) Weight (kg)
Electronics unit 18 36 21 9
Measurement chamber 8 9 11 2
Valve and cylinder panel 68 50 50 ~ 30
HPLC pump 14 26 42 10

*The temperature stability depends on variations in how the ambient affects the warming or cooling of the chamber. The specified temperature stability may not be reached if the room temperature changes more than ± 1° C, if there is a draft or a heat source nearby. The specifications above are valid for this configuration. All specifications are subject to change without notice.

Sensors

Standard sensors
The sensor is at the heart of the QCM-D experiment. Browse the widest range of sensors on the market to find out which sensor material and coating is best suited for your research.
We offer over 50 standard sensors - from various metals, oxides and carbides to polymers, functionalized coatings and and standardized soils. Our sensors are developed and produced to provide you with stable, reliable and reproducible data. Full performance is ensured through extensive quality controls and guaranteed for one-time use according to the recommendations.
Customized sensors
Sensor materials and coatings based on your specific needs
Read more

Want the see more?

Explore our sensors

Software

QSoft and Dfind software

QSense softwares are designed for you to make the most out of your QCM-D measurements. QSoft is collecting your data whereas Dfind makes your analysis easier. 

Dfind features

  • A complete analysis toolbox 
    One software for all your needs 
  • Intuitive interface 
    Dfind supports you all the way through your analysis process - from data preparation to final reporting
  • Guided modelling
    To take you through your analysis step by step 
  • Material library
    Configuring your modelling setup is easy, just select your sample material from the list
  • Autoplotting
    Visualizes your results throughout the whole analysis
  • Smart tools
    Dfind offers several analysis methods including shifts, rates and slopes to help you extract the information you need
  • Analyze all data in one go
    To save your time, Dfind allows you to review, model and analyze multiple data sets in one go
Would you like to know more about the details of Dfind and learn how the subscription works?

Learn more about Dfind!

Computer requirements

Required
  • PC with 64-bit Windows 7 SP1, 8, 8.1 or 10
  • At least 1366×768 px screen resolution
  • At least 4 GB RAM


Recommended
  • 1920×1080 Full HD screen resolution.
  • At least 8 GB RAM
  • At least 50 GB HD space
  • Core i5 5th generation Intel (or comparable) processor or better

Accessories

Add more possibilities

QSense High Pressure is based on our most versatile QCM-D instrument QSense Explorer. If you want to perform measurements in ambient pressure, you can always expand your possibilities with our Explorer chamber. We have selected a few add-ons you might be interested in.  

Testimonials

What others say

Our instruments are present at many prestigious universities and research facilities worldwide. Take a minute to find out what others say about QSense. 

citat8

Malkiat Johal on QSense

"I have found QSense to be one of the best techniques for an undergraduate lab because it’s turnkey and it requires very little maintenance."

Johal Malkiat-1

Malkiat Johal, Professor of Chemistry, Pomona College

"The operating principles are straightforward and the students can focus on the science. And so, that’s something that we have been really happy with, it really works in this kind of setting. It’s an ideal method for an undergraduate surface science lab."

citat8

Jodie Lutkenhaus on QSense

"We can monitor the mass change of our system in real-time. I can tell you that for every electron moved, this amount of mass changed. That’s powerful. You can’t really get that with any other system."

Jodie Lutkenhaus

Jodie Lutkenhaus, Associate Professor, Texas A&M University

"We use the QSense high temperature model that allows us to investigate polyelectrolyte complexes and their response to temperature. We’re also using the electrochemistry module so we can run our standard electrochemical measurements at the same time as we run the QCM-D."

citat8

Kenichi Sakai on QSense

"We regard QCM-D as a valuable measuring tool due to its high sensitivity and stability and find it applicable for versatile studies because of its availabilities of sensors with various different types of surfaces. In this context I would say QCM-D is the best suitable solution for simulating a variety of nanoscale interaction behaviors both real-time & in-situ.

Jodie Lutkenhaus-1

Kenichi Sakai, Associate Professor, Tokyo University of Science

"We are working on academic research in the field of colloid and interface chemistry and our main work is synthesis of novel surfactants and characterization of their properties. We use QCM-D as a must-tool to comprehend molecular adsorption/desorption behaviors specifically observed at a solid-liquid interface."

citat8

Marité Cárdenas on QSense

"QSense instruments are a great tool for our biophysical research. They enable rapid screening for biomolecular interaction at lipid bilayers and also allow optimising the parameters for deposition of thin films."

malmö universitet

Professor Dr. Marité Cárdenas, Health and Society, Malmö University

"The instrument is easy to use, and has a long working life as long as you follow the maintenance instructions! The technical staff at Biolin Scientific are a pleasure to work with: They are nice and always give quick feedback and support."

Knowledge

Learn more

We have gathered all our in-depth knowledge associated with QSense High Pressure. Browse around amongst guides, overviews and white papers to find a topic of interest. 

  • QSense
Guide

How to read a QCM Specification

There are key parameters to keep an eye on when investing in a new QCM instrument. Learn what they mean, and why they are important.

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  • QSense
Overview

Information Obtained with QSense QCM-D

We have summarized the parameters and processes that can be studied with QCM-D for you.

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  • QSense
White Paper

QCM-D vs other QCMs

We sort out the the differences between QCM methods to answer the question - does it matter which one I use?

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  • QSense
Overview

The Sauerbrey Relation

Time to learn how the Sauerbrey relation is derived and what the parameters mean.

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  • QSense
Guide

QCM-D Data Analysis

We put together guidelines for you on how to evaluate which method to use, and what happens if you choose the wrong approach.

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  • QSense
Overview

QCM-D Studies of Engineered Nanoparticles

In this overview we explore three examples of nanoparticle analysis with QCM-D.

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  • QSense
Guide

QSense Etching Guide

Learn how to use QSense technology for assessment of detergent etching properties.

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  • QSense
Overview

The Working Principles of QCM and QCM-D

Learn the fundamentals of how the technologies work, and what is the difference between them.

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  • QSense
Overview

What is Dissipation?

This is your chance to find out what it is, why it is important, and how it can be measured.

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  • QSense
Overview

Temperature Stability in QCM Measurements

Achieve reliable and reproducible QCM measurements by controlling the temperature.

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  • QSense
Guide

How to Generate Quality QCM-D Data

Follow our checklist for high-quality data and reproducible measurements.

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  • QSense
Overview

How QCM Results are Influenced by Layer Distribution

The distribution of the measured layer is key to your results. Discover why and how to handle it.

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  • QSense
Overview

What is Piezoelectricity?

Bone, wood and quartz are all piezoelectric materials. Learn about piezoelectricity and how it works

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  • QSense
Overview

QCM-D vs other QCMs

Let this brief overview guide you to your most suitable choice of QCM.

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  • QSense
Guide

How to Optimize the QCM-D Baseline Stability

9 steps to eliminate error sources and optimize reproducibility

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  • QSense
Overview

Characterization of Polymer-based Systems

Analyze layer build-up, conformation and molecular interaction with QSense QCM-D

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  • QSense
Case Study

Analysis of Surfactant-Surface Interactions with QSense

Find out how to analyze surfactant interaction with surfaces at the nanoscale.

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  • QSense
Overview

What is a Viscoelastic material?

Ice, wood and a disks in the human spine are all viscoelastic materials. What does it really mean?

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  • QSense
Overview

Characterization of Biomolecular Interactions

Learn how biomolecular interactions can be analyzed using QSense® QCM-D technology and what information you can get.

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  • QSense
Webinar

Dfind Basic Training Course

Learn the basics of Dfind, get a walk-through of the software and watch two live demo examples.

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  • QSense
Webinar

Basics of QCM-D

Learn the fundamentals of the technology, its possibilities and limitations and get a deeper understanding of nanometer layers.

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  • QSense
Webinar

Biomaterials – Man-made Materials for Regenerative Medicine

Learn from Prof. Bengt Kasemo in this webinar on Biomaterials – man-made materials for regenerative medicine.

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  • QSense
Webinar

QCM-D as a Tool to Study the Binding of Viruses

Hear researcher Gustaf Rydell, on how they used QCM-D to study interactions between virus particles and membrane associated glycolipids.

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  • QSense
Webinar

QCM-D for Bacterial Adhesion Studies

Listen to Adam Olsson, McGill University, about how they use QCM-D for bacterial adhesion studies.

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  • QSense
Webinar

Nanocellulose Research with QCM-D

Watch our webinar on Nanocellulose Research with QCM-D where we will discuss thin films of cellulose nanofibrils development, and their characterization. 

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  • QSense
Webinar

Using QCM-D in the Food Industry

Learn more about QCM-D in food industry with studies of shelf life from Cornell University.

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Webinar

Characterization of Surfaces and Surface Reactions in Energy Storage

Learn how QCM-D can be used to characterize surfaces and reactions for energy storage from Dr. Archana Jaiswal, Nanoscience Instruments.

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  • QSense
Webinar

How Excipients, Surfaces and Formulation Conditions Affect Therapeutic Proteins

Can QCM-D quantify how surfactants affect protein-surface interaction? Watch this webinar with Dr. Archana Jaiswal to find out more.

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  • QSense
Overview

What is Biocompatibility?

In this overview we explain how biocompatibility is defined and give examples of what the property entails.

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  • QSense
Overview

The Dissipation Factor in QCM-D Technology

In this overview, we take a closer look at the behavior of the sensor oscillation at various types of loads and investigate what the D-factor reveals.

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  • QSense
Overview

Why it is Useful to use Multiple Overtones in QCM Measurements?

Learn what information the overtones offer in this overview.

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  • QSense
Overview

QSense Analysis in CMP

In this overview, we present how QSense® QCM-D technology can be used in molecule-surface interaction analysis and optimization of CMP related processes.

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  • QSense
Overview

Why the Resonance Frequency of a QCM Sensor is 5MHz

What determines the value of the fundamental resonance frequency? In this overview, we explain the theory behind the number.

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  • Attension
Webinar

Working with QCM-D and Contact Angle Measurements under High Pressure - Oil and Gas Applications

Explore the possibilities of performing measurements in high pressure, techniques especially suitable for oil and gas applications.

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  • QSense
Webinar

Adsorption and aggregation of monoclonal antibodies at silicone oil-water interfaces

Learn more about adsorption and aggregation of monoclonal antibodies at silicone oil-water interfaces with Ph.D. Aadithya Kannan at Genentech.

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