QCM-D

QSense High Pressure

The system provides you with the opportunity to explore real-life conditions of high pressure and high temperature in your experimental set up.

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Guide

Overview

Most suitable when

You are striving to explore real-life high pressure and high temperature conditions
For the standard configuration the pressure and temperature can be set to a maximum of 200 Bar and 150 °C respectively, but the instrument can also be configured after your specific needs
You want to expand your possibilities
The system is built upon the versatile and modular QSense Explorer providing plenty of add-ons if you want to widen your view

A quick view

Get an overview of the QSense High Pressure system with this 2-minute video. Watch it in fullscreen for the best experience!

3 reasons to invest

Make smarter decisions

Whether you are struggling to increase oil yield, to prevent fouling of pipes or to find an optimal lubricant for engines, it is valuable to understand your processes better. With QSense High Pressure you can make smarter decisions based on information about the surface interaction processes that are key to your outcome.

Explore real-life conditions

We are providing standard and custom made sensors to fit your needs. Study what happens in real-time to draw conclusions and optimize your process based on QCM-D results. Analyzing under relevant conditions can make the whole difference. That is why we created the QSense High Pressure.

Add a highly sensitive tool

Recording the changes of frequency and dissipation of a quartz crystal sensor, the technology offers you a new set of eyes in the studies of surface events such as adsorption and desorption at the nanoscale.

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Specifications

A closer look

Let's dive into the specifications for QSense High Pressure.

Measurement range and capacity

Measurement channels	1
Working temperature*	4 to 150 °C, controlled via the software, stability ± 0.02 °C
Working pressure	90 to 200 bar (with the alternative peristaltic pump measurements can also be performed at ambient pressure)
Sensors (frequency range)	5 MHz (1-72)
Number of measured harmonics	7, allows for full viscoelastic modeling

Sample and fluidics

Minimum sample volume, stagnant mode	~ 40 μl
Minimum sample volume, flow mode	~ 200 μl
Flow rates	25-150 μl/min applicable for QSense setup (Peristaltic pump settable to 0-1 ml/min)

Performance characteristics

Maximum time resolution	300 datapoints per second (each datapoint represents an f and D value)
Sensitivity/limit of detection and noise	Refer to performance in different modes, for more info visit QSense Explorer product page
Long-term stability*	Frequency: < 1 Hz/h Dissipation: < 0.15∙10^-6 Temperature: < 0.02˚C/h

Software

	QSoft Acquisition software	Dfind Analysis software
Measurement channels	Time-resolved Frequency and Dissipation for 7 harmonics	Thickness (or mass), viscosity, shear modulus and the frequency dependence of the viscosity and shear modulus. Kinetics, slope, rise time and more
Computer requirements	USB 2.0	PC with 64-bit > 1366×768 px screen resolution, > 4 GB RAM
Operating system	Windows 10 or later (earlier Windows versions may not fully work and support cannot be guaranteed)
Import/export	Excel, BMP, JPG, WMF, GIF, PCX, PNG, TXT	CSV files. Decimal separator, full stop or comma

Electrical data QSense Electronics unit

Power supply and frequency

115-120 / 220 / 230-240 V AC, 50-60 Hz
The power supply should be properly grounded

Dimensions and weight

	Height (cm)	Width (cm)	Depth (cm)	Weight (kg)
Electronics unit	18	36	21	9
Measurement chamber	8	9	11	2
Valve and cylinder panel	68	50	50	~ 30
HPLC pump	14	26	42	10

*The temperature stability depends on variations in how the ambient affects the warming or cooling of the chamber. The specified temperature stability may not be reached if the room temperature changes more than ± 1° C, if there is a draft or a heat source nearby. The specifications above are valid for this configuration. All specifications are subject to change without notice.

Sensors

Standard sensors

The sensor is at the heart of the QCM-D experiment. Browse the widest range of sensors on the market to find out which sensor material and coating is best suited for your research.

We offer over 50 standard sensors - from various metals, oxides and carbides to polymers, functionalized coatings and and standardized soils. Our sensors are developed and produced to provide you with stable, reliable and reproducible data. Full performance is ensured through extensive quality controls and guaranteed for one-time use according to the recommendations.

Customized sensors

Sensor materials and coatings based on your specific needs

Stainless Steel SS2343

QSX 309

PS-Hydrophobic Polystyrene

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Software

QSoft and Dfind software

QSense softwares are designed for you to make the most out of your QCM-D measurements. QSoft is collecting your data whereas Dfind makes your analysis easier.

Dfind features

A complete analysis toolbox
One software for all your needs
Intuitive interface
Dfind supports you all the way through your analysis process - from data preparation to final reporting
Guided modelling
To take you through your analysis step by step
Material library
Configuring your modelling setup is easy, just select your sample material from the list
Autoplotting
Visualizes your results throughout the whole analysis
Smart tools
Dfind offers several analysis methods including shifts, rates and slopes to help you extract the information you need
Analyze all data in one go
To save your time, Dfind allows you to review, model and analyze multiple data sets in one go

Would you like to know more about the details of Dfind and learn how the subscription works?

Computer requirements

Required

PC with 64-bit Windows 7 SP1, 8, 8.1 or 10
At least 1366×768 px screen resolution
At least 4 GB RAM

Accessories

Add more possibilities

QSense High Pressure is based on our most versatile QCM-D instrument QSense Explorer. If you want to perform measurements in ambient pressure, you can always expand your possibilities with our Explorer chamber. We have selected a few add-ons you might be interested in.

Electrochemistry Module

For simultaneous QCM-D and electrochemistry measurements on the same surface. Enables cyclic voltammetry and electrochemical impedance measurements to explore polymer behavior, electrostatic interactions, corrosion etc.

Ellipsometry Module

Enables simultaneous QCM-D and ellipsometry measurements on the same surface, which allows for quantification of solvent content in the film. It also gives a refined analysis of the morphological changes of the adsorbed film.

Window Module

The Window Module allows optical access to the sensor surface through a sapphire window. It enables experiments with UV-induced reactions and when used in the QSense Explorer chamber, the compact design also enables microscopy studies of reactions on the sensor.

Configure QSense Explorer with accessories and modules in our Instrument Selector!

Testimonials

What others say

Our instruments are present at many prestigious universities and research facilities worldwide. Take a minute to find out what others say about QSense.

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Malkiat Johal on QSense

"I have found QSense to be one of the best techniques for an undergraduate lab because it’s turnkey and it requires very little maintenance."

Malkiat Johal, Professor of Chemistry, Pomona College

"The operating principles are straightforward and the students can focus on the science. And so, that’s something that we have been really happy with, it really works in this kind of setting. It’s an ideal method for an undergraduate surface science lab."

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Jodie Lutkenhaus on QSense

"We can monitor the mass change of our system in real-time. I can tell you that for every electron moved, this amount of mass changed. That’s powerful. You can’t really get that with any other system."

Jodie Lutkenhaus, Associate Professor, Texas A&M University

"We use the QSense high temperature model that allows us to investigate polyelectrolyte complexes and their response to temperature. We’re also using the electrochemistry module so we can run our standard electrochemical measurements at the same time as we run the QCM-D."

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Kenichi Sakai on QSense

"We regard QCM-D as a valuable measuring tool due to its high sensitivity and stability and find it applicable for versatile studies because of its availabilities of sensors with various different types of surfaces. In this context I would say QCM-D is the best suitable solution for simulating a variety of nanoscale interaction behaviors both real-time & in-situ.

Kenichi Sakai, Associate Professor, Tokyo University of Science

"We are working on academic research in the field of colloid and interface chemistry and our main work is synthesis of novel surfactants and characterization of their properties. We use QCM-D as a must-tool to comprehend molecular adsorption/desorption behaviors specifically observed at a solid-liquid interface."

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Marité Cárdenas on QSense

"QSense instruments are a great tool for our biophysical research. They enable rapid screening for biomolecular interaction at lipid bilayers and also allow optimising the parameters for deposition of thin films."

Professor Dr. Marité Cárdenas, Health and Society, Malmö University

"The instrument is easy to use, and has a long working life as long as you follow the maintenance instructions! The technical staff at Biolin Scientific are a pleasure to work with: They are nice and always give quick feedback and support."

Knowledge

Learn more

We have gathered all our in-depth knowledge associated with QSense High Pressure. Browse around amongst guides, overviews and white papers to find a topic of interest.

QSense

Guide

How to read a QCM Specification

There are key parameters to keep an eye on when investing in a new QCM instrument. Learn what they mean, and why they are important.

Download

QSense

Overview

Information Obtained with QSense QCM-D

We have summarized the parameters and processes that can be studied with QCM-D for you.

Most suitable when

A quick view

3 reasons to invest

Make smarter decisions

Explore real-life conditions

Add a highly sensitive tool

Download brochure

A closer look

Measurement range and capacity

Sample and fluidics

Performance characteristics

Software

Electrical data QSense Electronics unit

Dimensions and weight

Top suggestions

Want the see more?

QSoft and Dfind software

Dfind features

Computer requirements

Required

Recommended

Add more possibilities

Electrochemistry Module

Ellipsometry Module

Window Module

What others say

Malkiat Johal on QSense

Malkiat Johal, Professor of Chemistry, Pomona College

Jodie Lutkenhaus on QSense

Jodie Lutkenhaus, Associate Professor, Texas A&M University

Kenichi Sakai on QSense

Kenichi Sakai, Associate Professor, Tokyo University of Science

Marité Cárdenas on QSense

Professor Dr. Marité Cárdenas, Health and Society, Malmö University

Learn more

How to read a QCM Specification

Information Obtained with QSense QCM-D

QCM-D vs other QCMs

The Sauerbrey Relation

QCM-D Data Analysis

QCM-D Studies of Engineered Nanoparticles

QSense Etching Guide

The Working Principles of QCM and QCM-D

What is Dissipation?

Temperature Stability in QCM Measurements

How to Generate Quality QCM-D Data

How QCM Results are Influenced by Layer Distribution

What is Piezoelectricity?

QCM-D vs other QCMs

How to Optimize the QCM-D Baseline Stability

Characterization of Polymer-based Systems

Analysis of Surfactant-Surface Interactions with QSense

What is a Viscoelastic material?

Characterization of Biomolecular Interactions

Dfind Basic Training Course

Basics of QCM-D

Biomaterials – Man-made Materials for Regenerative Medicine

QCM-D as a Tool to Study the Binding of Viruses

QCM-D for Bacterial Adhesion Studies

Nanocellulose Research with QCM-D

Using QCM-D in the Food Industry

Characterization of Surfaces and Surface Reactions in Energy Storage

How Excipients, Surfaces and Formulation Conditions Affect Therapeutic Proteins

What is Biocompatibility?

The Dissipation Factor in QCM-D Technology

Why it is Useful to use Multiple Overtones in QCM Measurements?

QSense Analysis in CMP

Why the Resonance Frequency of a QCM Sensor is 5MHz

Working with QCM-D and Contact Angle Measurements under High Pressure - Oil and Gas Applications

Adsorption and aggregation of monoclonal antibodies at silicone oil-water interfaces

QSense High Pressure

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