- A complete analysis toolbox
One software for all your needs - Intuitive interface
Dfind supports you all the way through your analysis process - from data preparation to final reporting - Guided modelling
To take you through your analysis step by step - Material library
Configuring your modelling setup is easy, just select your sample material from the list - Autoplotting
Visualizes your results throughout the whole analysis - Smart tools
Dfind offers several analysis methods including shifts, rates and slopes to help you extract the information you need - Analyze all data in one go
To save your time, Dfind allows you to review, model and analyze multiple data sets in one go
- Products
- QSense
- QCM-D Instruments
- QSense High Pressure
QCM-D
QSense High Pressure
The system provides you with the opportunity to study molecular interactions at surfaces and interfaces in real-time, exploring real-life conditions of high pressure and high temperature in your experimental set up.
phenomena
-
Adsorption
-
Desorption
-
Binding and interactions
-
Swelling
-
De-swelling, crosslinking and collapse
-
Degradation, corrosion and etching
Measure in High Pressure & Temperature
Key features
-
Measure mass, thickness, and viscoelastic properties of rigid and soft films
7-harmonic QCM-D with QSense Decay technology enables qualitative and quantitative analysis -
High temperature chamber
Measure up to 150°C -
Maintain liquid phase
Use pressure to maintain liquid state in higher temperatures -
High pressure module
Measure between 90-200 bar to explore real-life pressure conditions -
Full high pressure set up
All you need to be able to work with liquid flow at high pressures -
Broadest offer of sensor surfaces and coatings
Set up model systems that are as close as possible to real-world conditions
QSOFT AND DFIND SOFTWARE
QSense software is tailored to help you maximize the potential of your QCM-D measurements. With QSoft capturing your data and Dfind simplifying your analysis, you can streamline your research process effortlessly.
measurement conditions
-
Flow mode
-
Stagnant mode
-
Liquid phase
-
Harsh chemicals
-
Low temperature
-
High temperature
-
Variable pressure
A closer look
Let's dive into the specifications for QSense High Pressure.
Measurement range and capacity
Measurement channels | 1 |
Working temperature* | 4 to 150 °C, controlled via the software, stability ± 0.02 °C |
Working pressure | 90 to 200 bar (with the alternative peristaltic pump measurements can also be performed at ambient pressure) |
Sensors (frequency range) | 5 MHz (1-72) |
Number of measured harmonics |
7, allows for full viscoelastic modeling |
Sample and fluidics
Minimum sample volume, stagnant mode | ~ 40 μl |
Minimum sample volume, flow mode | ~ 200 μl |
Flow rates | 25-150 μl/min applicable for QSense setup (Peristaltic pump settable to 0-1 ml/min) |
Additional info | Note that the system liquid to be used in the QSense High Pressure System may require a fume hood or point exhaustion |
Performance characteristics
Maximum time resolution | 300 datapoints per second (each datapoint represents an f and D value) |
Sensitivity/limit of detection and noise | Refer to performance in different modes, for more info visit QSense Explorer product page |
Long-term stability* | Frequency: < 1 Hz/h Dissipation: < 0.15∙10-6 Temperature: < 0.02˚C/h |
*The temperature stability depends on variations in how the ambient affects the warming or cooling of the chamber. The specified temperature stability may not be reached if the room temperature changes more than ± 1° C, if there is a draft or a heat source nearby. The specifications above are valid for this configuration. All specifications are subject to change without notice.
QSoft and Dfind software
QSense softwares are designed for you to make the most out of your QCM-D measurements. QSoft is collecting your data whereas Dfind makes your analysis easier.
Dfind features
Computer requirements
Required
- PC with 64-bit Windows 7 SP1, 8, 8.1 or 10
- At least 1366×768 px screen resolution
- At least 4 GB RAM
Recommended
- 1920×1080 Full HD screen resolution.
- At least 8 GB RAM
- At least 50 GB HD space
- Core i5 5th generation Intel (or comparable) processor or better
Electrochemistry Module
For simultaneous QCM-D and electrochemistry measurements on the same surface. Enables cyclic voltammetry and electrochemical impedance measurements to explore polymer behavior, electrostatic interactions, corrosion etc.
Ellipsometry Module
Enables simultaneous QCM-D and ellipsometry measurements on the same surface, which allows for quantification of solvent content in the film. It also gives a refined analysis of the morphological changes of the adsorbed film.
Window Module
The Window Module allows optical access to the sensor surface through a sapphire window. It enables experiments with UV-induced reactions and when used in the QSense Explorer chamber, the compact design also enables microscopy studies of reactions on the sensor.
What our customers say
Our instruments are present at many prestigious universities and research facilities worldwide. Take a minute to find out what others say about QSense High Pressure.
Prof. Dennis R. Heldman, The Ohio State University
"Our laboratory uses the QSense High Pressure QCM-D system for the study of the reactions occurring at the interface between a surface and a high-protein liquid food. Information about the rate of fouling on the surface and the composition of the foulant has provided new and important insights before scale-up to pilot and commercial-scale experiments with a focus on the contributions of flow characteristics over the surface. These new and different insights provide our laboratory and others with a completely new and different dimension to our research.”
The Ohio State University
Ohio State University, OSU, is the highest-ranked public university in Ohio and home to the Department of Food Science and Technology. The work of Prof. Dennis R. Heldman centers around food engineering, with emphasis on process design to achieve maximum efficiency and optimum food product quality.
Learn more
We have gathered all our in-depth knowledge associated with QSense High Pressure. Browse around amongst guides, overviews and white papers to find a topic of interest.
- QSense
How Excipients, Surfaces and Formulation Conditions Affect Therapeutic Proteins
- QSense
Basics of QCM-D
- QSense
How to Optimize the QCM-D Baseline Stability
- QSense
The Working Principles of QCM and QCM-D
- QSense
QCM-D vs other QCMs
- QSense
What is Piezoelectricity?
- QSense
How QCM Results are Influenced by Layer Distribution
- QSense
Why the Resonance Frequency of a QCM Sensor is 5MHz
- QSense
Characterization of Polymer-based Systems
- QSense
Using QCM-D in the Food Industry
- QSense
What is Biocompatibility?
- QSense
Why it is Useful to use Multiple Overtones in QCM Measurements?
- QSense
Nanocellulose Research with QCM-D
- QSense
Analysis of Surfactant-Surface Interactions with QSense
- QSense
Getting Started with QSense Dfind
- QSense
QCM-D Data Analysis
- QSense
QCM-D as a Tool to Study the Binding of Viruses
- QSense
Characterization of Surfaces and Surface Reactions in Energy Storage
- QSense
QSense Etching Guide
- QSense
QCM-D Characterization of Antimicrobial Lipid Interactions with Supported Lipid Bilayers: Towards Antiviral Applications in the Biomedical and Agricultural Sectors
- QSense
The Sauerbrey Relation
- QSense
QCM-D Studies of Engineered Nanoparticles
- QSense
Characterization of Biomolecular Interactions
- Attension
Working with QCM-D and Contact Angle Measurements under High Pressure - Oil and Gas Applications
- QSense
Adsorption and Aggregation of Monoclonal Antibodies at Silicone Oil-Water Interfaces
- QSense
QSense Analysis in CMP
- QSense
The Dissipation Factor in QCM-D Technology
- QSense
Temperature Stability in QCM Measurements
- QSense
What is Dissipation?
- QSense
What is a Viscoelastic material?
- QSense
How to Generate Quality QCM-D Data
- QSense
QCM-D vs other QCMs
- QSense
QCM-D Publications in Battery Research
- QSense
How to read a QCM Specification
- QSense
Dfind Basic Training Course
- QSense
Information Obtained with QSense QCM-D
- QSense