Nanoparticle suspensions are complex systems and their characterization includes several parameters such as size, concentration in solution, shape, surface charge and chemical composition. To collect this information, an arsenal of techniques is needed. Each technology will have a range of applications but also limitations which need to be kept in mind. Another aspect that needs to be considered is the fact that the characterization methods will provide information either at the ensemble level or at the single nanoparticle level.
So, what are the tools necessary to map the physical and chemical properties of nanoparticle suspensions? Here we have created an overview of nanoparticle characterization methods that could be used. The tools listed in the overview are examples of instruments that could answer the following key questions:
What is the size of my nanoparticles?
Which nanoparticle concentration do I have?
What is the shape of my nanoparticles?
What is the surface charge of my nanoparticles?
What are the bulk and surface chemical compositions of my nanoparticles?
Nanomaterials have found their way into ordinary products such as foods, cosmetics, and sportswear. Why did ‘nano’ become so popular? And what risks are involved when getting exposed to these nanoengineered entities?
To avoid potential adverse effects, it is relevant to study how nanoparticles interact with their surroundings. Here we present examples of how nanoparticle interaction with a variety of surfaces can be analyzed.
Nanoparticle suspensions are complex systems, and understanding their interaction with their environment requires characterization of a broad range of physicochemical properties. Here we present an overview of the key parameters that can be used to profile nanoparticle suspensions.
Déborah graduated in biophysics in 2015. Her PhD focused on building new tools and methods to characterize biological nanoparticles called extracellular vesicles. She is passionate about seeing the big picture in the small details and the small details in the big picture.