Surfactants are amphiphilic molecules that are used in several industrial processes and products to reduce surface and interfacial tension. Surfactants work as emulsifiers, wetting agents, and lubricants to name a few. Traditional surfactants cause a significant environmental issue as they accumulate in soil and water ecosystems. In addition, their usage in the food, pharmaceutical, and cosmetic industries is limited due to their toxic nature. For these reasons, biosurfactants have gained a lot of attention as a less toxic alternative to chemical surfactants.
Surfactants are amphiphilic molecules that include hydrophilic and hydrophobic parts. When in liquid, they orient themselves so that the hydrophilic part is in an aqueous solution and the hydrophobic part in air or oil. Surfactants are used in many industrial processes to reduce the surface or interfacial tension of the system. Surface tension decreases up to a point when micelles start to form. This point is called critical micelle concentration.
Biosurfactants have similar functionality as their chemical counterparts, but they are biological in nature. Biosurfactants are produced by a wide range of microorganisms such as bacteria, fungi, and yeast. The main advantage of biosurfactants is that they are environmentally friendly, less toxic, and biodegradable.
Chemical surfactants are typically classified based on the electric charge of the polar head group. Biosurfactants on the other hand are often divided based on their molecular weight to low- or high-molecular-weight. Molecules such as glycolipids and lipopeptides belong under low-molecular-weight and polysaccharides and proteins form the high-molecular-weight group.
The use of biosurfactants has been studied in multiple different industries. Due to their non-toxic or less-toxic nature, their use in the cosmetic, food, and pharmaceutical industries is especially of interest. In the pharmaceutical and medical industries, the diverse activities of biosurfactants such as anticancer, anti-inflammatory, and antiviral have further increased their appeal. Biosurfactants are also utilized in the petroleum industry in the bioremediation of oil spills.
QCM-D is utilized to understand the compatibility and to identify solution and excipient conditions that minimize the adsorption of therapeutic proteins
Micellar water is a clear, water-like liquid that contain one or several different types of surfactants.
Surfactants are utilized in numerous products from cleaning formulations to paints and pesticides.
Surfactants reduce the surface tension of solutions but can also change the wettability of solids.
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Soil removal efficiency of a formulation is typically assessed by running a cleaning test followed by an analysis of the result. Here we show how these two steps can be run simultaneously.
Here we present a summary of how protein adsorption to a silicone oil/water interface was analyzed in the presence and absence of surfactant.